4 ms·

One could eat healthy instead of course but hey, the good life.

shlant 3mo ago
you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better? Do you have the same simplistic ideas about GLP-1's?
- moi2388 3mo ago
  For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more.
  - pinkmuffinere 3mo ago
    The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs [1] https://my.clevelandclinic.org/health/articles/16867-cholesterol--nutrition-tlc https://my.clevelandclinic.org/health/articles/16867-cholest...
    - jghn 3mo ago
      Dietary cholesterol has little impact on blood cholesterol. However the post that started this debate mentioned mass loss. And that does have a decent correlation. Go from obese to not obese and the median person's cholesterol will drop quite a bit.
      - pinkmuffinere 3mo ago
        It’s possible the comments have changed, but I see nothing in the thread about mass loss. I do agree about weight though — losing weight is largely diet. > Go from obese to not obese and the median person's cholesterol will drop quite a bit. This is really interesting, I don’t think I’ve heard that before. Do you have a source you could share? Edit: this doesn’t necessarily prove you wrong, but this paper argues there’s little correlation between bmi and cholesterol [1] [1] https://link.springer.com/article/10.1007/s11695-010-0170-7 https://link.springer.com/article/10.1007/s11695-010-0170-7
        jghn 3mo ago
        for the most part mass == weight on Earth. Triglycerides & HDL are affected by weight (tho more triglycerides than anything else), e.g. Wing 2011.
        pinkmuffinere 3mo ago
        > for the most part mass == weight on Earth. The thread above us discusses neither mass nor weight. Here it is copied in full -- I encourage you to use ctrl-f > mediumsmart 1 hour ago > One could eat healthy instead of course but hey, the good life. > shlant 1 hour ago > you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better? > Do you have the same simplistic ideas about GLP-1's? > moi2388 1 hour ago > For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more I'm a bit upset that I put in effort to genuinely engage in your claims, and you're not willing to go back and read the thread to confirm claims that _you made_. In fact, you suckered me into re-reading the same thread _for the third time_ looking for some throwaway line I missed about mass or weight. I could just decide that internet discussion doesn't matter, and stop engaging on HN, but I'd rather not do that. Can you please try a bit more? I'm not going to reply to the Triglycerides & HDL comment without a link. It was your claim initially, and I was nice enough to provide a link with evidence against it, so surely you can do the same in support.
        jghn 3mo ago
        [flagged]
        rubiquity 3mo ago
        There isn't. I'm 15% body fat, eat healthy (avoid saturated fats, prioritize fiber), exercise 5-6 times per week, and have hypercholesterolemia. I, along with my parents, have very high LDL and ApoB and nothing I can do about it in terms of diet, exercise, or weight. I'm also not uncommon. They suspect as much of 30% of the population could be like this. There's a lot of ignorance in this thread.
    - moi2388 3mo ago
      I was responding to the glp-1 question. And yes, exercising and dieting absolutely reduces the need for these medications. It also reduces the amount of people who have high cholesterol, although again, in both cases not all
    - sn9 3mo ago
      Fiber intake has a dose-dependent effect on cholesterol levels. Obviously some people still need medication if they have particularly unfortunate genetics.
  - shlant 2mo ago
    wow you figured it out! but wait.. if it's that easy why is obesity such a huge issue?
nozzlegear 3mo ago
You wouldn't tell someone with diabetes or asthma to just live healthier and avoid their medication. There's nothing wrong with taking a pill, we're not cavemen living off the land.
- deleted 3mo ago
  [deleted]
deanc 3mo ago
Many people have high cholesterol due to genetics. In these cases even if you ate a 100% perfect diet it would only impact 25% of your cholesterol levels - which any physician would not be satisfied with.
- h2aichat 3mo ago
  That's the good news! It fixes that genetic problem (PCSK9 Inhibitor)
weregiraffe 3mo ago
You will still die you know, no matter your diet. And no god will reward your righteous corpse for eating healthy.
mediumsmart 3mo ago
eat healthy as in: only once a day and only six days a week. only water for drinking and only fresh stuff to eat, no meat, no eggs, nothing cooked, nothing baked, nothing fried, nothing grilled, nothing processed, no sugar and no salt. Being a major shift from the good life one should start it with a 7 day water fast. (do I have to say "ask your doctor before embarking"? done)
- HackerThemAll 3mo ago
  Yeah, when you grow up, get back to this comment to look how childish it is.
  - mediumsmart 3mo ago
    https://www.youtube.com/watch?v=RuOvn4UqznU https://www.youtube.com/watch?v=RuOvn4UqznU
jms703 3mo ago
Lose weight, yes. Exercise, yes. Accept a potentially fatal genetic defect when an option is available? No. Advise not callously generalizing your opinion on things like this. It's clear that you either spoke without knowing more, which happens, or you really don't seem to care to know more. I hope you're not in the latter.
preg_match 3mo ago
Eating healthy is a sub-optimal solution. Typically we see the most significant results with lifestyle changes + medical interventions and pharmaceuticals - more than either alone. There's a strange belief, I believe most born out of morality, that medicine undermines discipline or healthy lifestyle. But it does not, they work in tandem, each making the other stronger. It is true that taking medication is "easy" - not that easy, though. But easy != evil or immortal. If it's so easy, that's a good thing. It means we can stack it on top of lifestyle changes for very little marginal cost. If you're already working out and eating good, that's great. Go to your cardiologist and see if you're a candidate for statins or hypertension medication.

you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better? Do you have the same simplistic ideas about GLP-1's?

moi2388 3mo ago
For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more.
- pinkmuffinere 3mo ago
  The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs [1] https://my.clevelandclinic.org/health/articles/16867-cholesterol--nutrition-tlc https://my.clevelandclinic.org/health/articles/16867-cholest...
  - jghn 3mo ago
    Dietary cholesterol has little impact on blood cholesterol. However the post that started this debate mentioned mass loss. And that does have a decent correlation. Go from obese to not obese and the median person's cholesterol will drop quite a bit.
    - pinkmuffinere 3mo ago
      It’s possible the comments have changed, but I see nothing in the thread about mass loss. I do agree about weight though — losing weight is largely diet. > Go from obese to not obese and the median person's cholesterol will drop quite a bit. This is really interesting, I don’t think I’ve heard that before. Do you have a source you could share? Edit: this doesn’t necessarily prove you wrong, but this paper argues there’s little correlation between bmi and cholesterol [1] [1] https://link.springer.com/article/10.1007/s11695-010-0170-7 https://link.springer.com/article/10.1007/s11695-010-0170-7
      - jghn 3mo ago
        for the most part mass == weight on Earth. Triglycerides & HDL are affected by weight (tho more triglycerides than anything else), e.g. Wing 2011.
        pinkmuffinere 3mo ago
        > for the most part mass == weight on Earth. The thread above us discusses neither mass nor weight. Here it is copied in full -- I encourage you to use ctrl-f > mediumsmart 1 hour ago > One could eat healthy instead of course but hey, the good life. > shlant 1 hour ago > you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better? > Do you have the same simplistic ideas about GLP-1's? > moi2388 1 hour ago > For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more I'm a bit upset that I put in effort to genuinely engage in your claims, and you're not willing to go back and read the thread to confirm claims that _you made_. In fact, you suckered me into re-reading the same thread _for the third time_ looking for some throwaway line I missed about mass or weight. I could just decide that internet discussion doesn't matter, and stop engaging on HN, but I'd rather not do that. Can you please try a bit more? I'm not going to reply to the Triglycerides & HDL comment without a link. It was your claim initially, and I was nice enough to provide a link with evidence against it, so surely you can do the same in support.
        jghn 3mo ago
        [flagged]
      - rubiquity 3mo ago
        There isn't. I'm 15% body fat, eat healthy (avoid saturated fats, prioritize fiber), exercise 5-6 times per week, and have hypercholesterolemia. I, along with my parents, have very high LDL and ApoB and nothing I can do about it in terms of diet, exercise, or weight. I'm also not uncommon. They suspect as much of 30% of the population could be like this. There's a lot of ignorance in this thread.
  - moi2388 3mo ago
    I was responding to the glp-1 question. And yes, exercising and dieting absolutely reduces the need for these medications. It also reduces the amount of people who have high cholesterol, although again, in both cases not all
  - sn9 3mo ago
    Fiber intake has a dose-dependent effect on cholesterol levels. Obviously some people still need medication if they have particularly unfortunate genetics.
- shlant 2mo ago
  wow you figured it out! but wait.. if it's that easy why is obesity such a huge issue?

nozzlegear 3mo ago

You wouldn't tell someone with diabetes or asthma to just live healthier and avoid their medication. There's nothing wrong with taking a pill, we're not cavemen living off the land.

deleted 3mo ago
[deleted]

deanc 3mo ago

Many people have high cholesterol due to genetics. In these cases even if you ate a 100% perfect diet it would only impact 25% of your cholesterol levels - which any physician would not be satisfied with.

h2aichat 3mo ago
That's the good news! It fixes that genetic problem (PCSK9 Inhibitor)

weregiraffe 3mo ago

You will still die you know, no matter your diet. And no god will reward your righteous corpse for eating healthy.

mediumsmart 3mo ago

eat healthy as in: only once a day and only six days a week. only water for drinking and only fresh stuff to eat, no meat, no eggs, nothing cooked, nothing baked, nothing fried, nothing grilled, nothing processed, no sugar and no salt. Being a major shift from the good life one should start it with a 7 day water fast. (do I have to say "ask your doctor before embarking"? done)

HackerThemAll 3mo ago
Yeah, when you grow up, get back to this comment to look how childish it is.
- mediumsmart 3mo ago
  https://www.youtube.com/watch?v=RuOvn4UqznU https://www.youtube.com/watch?v=RuOvn4UqznU

jms703 3mo ago

Lose weight, yes. Exercise, yes. Accept a potentially fatal genetic defect when an option is available? No. Advise not callously generalizing your opinion on things like this. It's clear that you either spoke without knowing more, which happens, or you really don't seem to care to know more. I hope you're not in the latter.

preg_match 3mo ago

Eating healthy is a sub-optimal solution. Typically we see the most significant results with lifestyle changes + medical interventions and pharmaceuticals - more than either alone. There's a strange belief, I believe most born out of morality, that medicine undermines discipline or healthy lifestyle. But it does not, they work in tandem, each making the other stronger. It is true that taking medication is "easy" - not that easy, though. But easy != evil or immortal. If it's so easy, that's a good thing. It means we can stack it on top of lifestyle changes for very little marginal cost. If you're already working out and eating good, that's great. Go to your cardiologist and see if you're a candidate for statins or hypertension medication.