I pass from markdown to typst pdf via pandoc a few times a day. From that point of view it is just an alternative to latex or roff, e.g. pandoc -r markdown -w

I pass from markdown to typst pdf via pandoc a few times a day. From that point of view it is just an alternative to latex or roff, e.g. pandoc -r markdown -w pdf --pdf-engine=typst input.md -o output.pdf