3 ms·

No, not just weeding out due to Covid. If that was the case, you won't see death rates decrease across multiple groups and not just the weakest groups. > Dea

No, not just weeding out due to Covid. If that was the case, you won't see death rates decrease across multiple groups and not just the weakest groups. > Death rates declined across all racial and ethnic groups, and in both men and women. https://www.medpagetoday.com/publichealthpolicy/publichealth/119643 https://www.medpagetoday.com/publichealthpolicy/publichealth... > It's the result of not only the dissipation of the COVID-19 pandemicopens in a new tab or window, but also waning death rates from all the nation's top killers, including heart disease, cancer, and drug overdoses.

klooney 8mo ago
GLP1 theory of everything
- Balgair 8mo ago
  https://www.drugdiscoverytrends.com/top-25-drugs-by-sales-2025-h1/ https://www.drugdiscoverytrends.com/top-25-drugs-by-sales-20... Obesity drugs are in the top 25 for 2025, but don't make up the largest plurality. That goes to oncology drugs at ~1/3rd. Obesity drugs are at ~14%. I want to mention here that these oncology drugs are mostly antibody methods. Which, what the hell? We're making antibody drugs at scale now?! And that's like some of the highest selling drugs out there? For comparison, though not in the linked article here, Acetaminophen (Tylenol) only comes in at ~$4.3B, which would put it way down in 13th place, out of the top 10. Granted, this is sales numbers, and in the US, that's practically taking the savings of very sick people and turning it into stocks. Something that elicits no small reaction here on HN or just about anywhere. Still, to the point of the main article, yes, we live in an age of medical miracles, and it arrived quite suddenly, only in the last 7 years or so, and we have a lot of gas in this tank.
deleted 8mo ago
[deleted]
pinkmuffinere 8mo ago
I think it would depend on how the “weakest groups” are decided. If the weakest 10% of 2021 all died, then the weakest 10% of 2022 will be people who were stronger than 2021’s weakest 10%. All the groups would propagate up to be stronger than in previous years. Now i don’t know how these groups are drawn, percentiles is just what makes intuitive sense to me. The linked quotes don’t seem to support your argument, unless I misunderstand? If the weakest people die, then the remaining people are expected to be more resilient to heart disease and cancer. I think decreases in drug overdose and suicide are probably the most isolated from this effect, so I have higher confidence that those decreases are “real”. But I can imagine ways that even they might interact.

klooney 8mo ago

GLP1 theory of everything

Balgair 8mo ago
https://www.drugdiscoverytrends.com/top-25-drugs-by-sales-2025-h1/ https://www.drugdiscoverytrends.com/top-25-drugs-by-sales-20... Obesity drugs are in the top 25 for 2025, but don't make up the largest plurality. That goes to oncology drugs at ~1/3rd. Obesity drugs are at ~14%. I want to mention here that these oncology drugs are mostly antibody methods. Which, what the hell? We're making antibody drugs at scale now?! And that's like some of the highest selling drugs out there? For comparison, though not in the linked article here, Acetaminophen (Tylenol) only comes in at ~$4.3B, which would put it way down in 13th place, out of the top 10. Granted, this is sales numbers, and in the US, that's practically taking the savings of very sick people and turning it into stocks. Something that elicits no small reaction here on HN or just about anywhere. Still, to the point of the main article, yes, we live in an age of medical miracles, and it arrived quite suddenly, only in the last 7 years or so, and we have a lot of gas in this tank.

deleted 8mo ago

[deleted]

pinkmuffinere 8mo ago

I think it would depend on how the “weakest groups” are decided. If the weakest 10% of 2021 all died, then the weakest 10% of 2022 will be people who were stronger than 2021’s weakest 10%. All the groups would propagate up to be stronger than in previous years. Now i don’t know how these groups are drawn, percentiles is just what makes intuitive sense to me. The linked quotes don’t seem to support your argument, unless I misunderstand? If the weakest people die, then the remaining people are expected to be more resilient to heart disease and cancer. I think decreases in drug overdose and suicide are probably the most isolated from this effect, so I have higher confidence that those decreases are “real”. But I can imagine ways that even they might interact.