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> I am not saying that LLMs are worthless—they are marvels of engineering and can solve some particularly thorny problems that have confounded us for decades.

> I am not saying that LLMs are worthless—they are marvels of engineering and can solve some particularly thorny problems that have confounded us for decades. Disagree with that, because firstly, they have not really solved any problems that outweight the negatives that they have unleashed and will unleash on society. So they make programmers more effective: is that actually a good thing, though? Fact is, most software is designed to make consumerism and corporations more effective, and that's not really a good thing for the long-term health of the planet. Your article also indicates a sort of independence between keeping intellectual tasks primarily human and allowing AI/LLMs to work in specific domains. However, those with the power don't care about principles. They just want to replace as much as they can and use the human instinct to get ahead quickly to do so. And no amount of priniciple will stop them. AI is just too powerful to be used in a way that is consistent with human beings keeping their intellectual environment healthy.

stronglikedan 1y ago
> Disagree with that...they have not really solved any problems that outweight the negatives And I disagree with that. They are marvels of engineering and they have solved thorny problems. Just because they problems they've solved in the very short time they've been solving problems don't yet outweigh the negatives, doesn't mean they won't soon, and doesn't make either statement false. Great things take time, and great omelets are made from broken eggs. Nothing new under the sun, except AI.
- vouaobrasil 1y ago
  > they have solved thorny problems. Like what then? Let's hear some examples.
  - glial 1y ago
    For the sake of argument, here's one: > https://www.nature.com/articles/s41586-023-06924-6 https://www.nature.com/articles/s41586-023-06924-6
    - vouaobrasil 1y ago
      You can't be serious. This is a highly specialized field in a topic that a few dozen people have interest in. Rather useless and basically a mental stimulating game for some professors. I have a math PhD and know very well that math went well past its point of diminishing returns in solving real-world problems a long time ago.
      - glial 1y ago
        You asked for a thorny problem, and that is one. Whether it's significant by some other metric you didn't specify is a separate question.
  - rpdillon 1y ago
    Not going to do all your legwork for you, but there are tons of fields that are changing rapidly because of AI. In Material Science, there's a thorny problem of how to accelerate material development, or even how to perform non-destructive testing of materials. > AI, primarily through generative AI models, has dramatically changed our approach by accelerating the design process significantly. These models can predict material properties from extensive datasets, enabling rapid prototyping and evaluation that used to take years. We can now iterate designs quickly, focusing on the most promising materials early in the development phase, enhancing both efficiency and creativity in materials science. This is a huge leap forward because it reduces the time and cost associated with traditional materials development, allowing for more experimentation and innovation. > One notable application is using deep learning models to infer the internal properties of materials from surface data. This technology is groundbreaking, particularly for industries like aerospace and biomedical, where non-destructive testing is crucial. These models can predict internal flaws or stresses by analyzing external properties without physically altering the material. This capability is essential for maintaining the integrity of critical structures and devices, making materials safer and more reliable while saving time and resources. Other recent advances are in multimodal AI, where such models can design materials and understand and generate multiple input and output types, such as text, images, chemical formulas, microstructural designs, and much more. https://professional.mit.edu/news/articles/revolutionizing-materials-science-interview-markus-buehler-impact-ai https://professional.mit.edu/news/articles/revolutionizing-m... There's lots of other examples. New ways to create COVID vaccines: https://www.nature.com/articles/s41586-025-09442-9 https://www.nature.com/articles/s41586-025-09442-9 More effective than humans at reading medical scans: https://www.weforum.org/stories/2025/03/ai-transforming-global-health/ https://www.weforum.org/stories/2025/03/ai-transforming-glob... AI is already intensely useful, and will only continue to improve.
    - luanallnllm 1y ago
      All examples you linked are speculation on proof of concept work and none is about LLMs.
      - rpdillon 1y ago
  - polynomial 1y ago
    Apparently they have made HUGE breakthroughs in Online Bin Packing. Extremely Bullish.

stronglikedan 1y ago

> Disagree with that...they have not really solved any problems that outweight the negatives And I disagree with that. They are marvels of engineering and they have solved thorny problems. Just because they problems they've solved in the very short time they've been solving problems don't yet outweigh the negatives, doesn't mean they won't soon, and doesn't make either statement false. Great things take time, and great omelets are made from broken eggs. Nothing new under the sun, except AI.

vouaobrasil 1y ago
> they have solved thorny problems. Like what then? Let's hear some examples.
- glial 1y ago
  For the sake of argument, here's one: > https://www.nature.com/articles/s41586-023-06924-6 https://www.nature.com/articles/s41586-023-06924-6
  - vouaobrasil 1y ago
    You can't be serious. This is a highly specialized field in a topic that a few dozen people have interest in. Rather useless and basically a mental stimulating game for some professors. I have a math PhD and know very well that math went well past its point of diminishing returns in solving real-world problems a long time ago.
    - glial 1y ago
      You asked for a thorny problem, and that is one. Whether it's significant by some other metric you didn't specify is a separate question.
- rpdillon 1y ago
  Not going to do all your legwork for you, but there are tons of fields that are changing rapidly because of AI. In Material Science, there's a thorny problem of how to accelerate material development, or even how to perform non-destructive testing of materials. > AI, primarily through generative AI models, has dramatically changed our approach by accelerating the design process significantly. These models can predict material properties from extensive datasets, enabling rapid prototyping and evaluation that used to take years. We can now iterate designs quickly, focusing on the most promising materials early in the development phase, enhancing both efficiency and creativity in materials science. This is a huge leap forward because it reduces the time and cost associated with traditional materials development, allowing for more experimentation and innovation. > One notable application is using deep learning models to infer the internal properties of materials from surface data. This technology is groundbreaking, particularly for industries like aerospace and biomedical, where non-destructive testing is crucial. These models can predict internal flaws or stresses by analyzing external properties without physically altering the material. This capability is essential for maintaining the integrity of critical structures and devices, making materials safer and more reliable while saving time and resources. Other recent advances are in multimodal AI, where such models can design materials and understand and generate multiple input and output types, such as text, images, chemical formulas, microstructural designs, and much more. https://professional.mit.edu/news/articles/revolutionizing-materials-science-interview-markus-buehler-impact-ai https://professional.mit.edu/news/articles/revolutionizing-m... There's lots of other examples. New ways to create COVID vaccines: https://www.nature.com/articles/s41586-025-09442-9 https://www.nature.com/articles/s41586-025-09442-9 More effective than humans at reading medical scans: https://www.weforum.org/stories/2025/03/ai-transforming-global-health/ https://www.weforum.org/stories/2025/03/ai-transforming-glob... AI is already intensely useful, and will only continue to improve.
  - luanallnllm 1y ago
    All examples you linked are speculation on proof of concept work and none is about LLMs.
    - rpdillon 1y ago
- polynomial 1y ago
  Apparently they have made HUGE breakthroughs in Online Bin Packing. Extremely Bullish.