3 ms·
this is such an interesting problem. Imagine expanding the input size to 3.2Gbp, the size of human genome. I wonder if previously unimaginable interactions woul
by seydor 1y ago
this is such an interesting problem. Imagine expanding the input size to 3.2Gbp, the size of human genome. I wonder if previously unimaginable interactions would occur. Also interesting how everything revolves around U-nets and transformers these days.
- teaearlgraycold 1y ago> Also interesting how everything revolves around U-nets and transformers these days. To a man with a hammer…
- SV_BubbleTime 1y agoSoon we’ll be able to get the whole genome up on the blockchain. (I thought the /s was obvious)
- TeMPOraL 1y agoOr to a man with a wheel and some magnets and copper wire... There are technologies applicable broadly, across all business segments. Heat engines. Electricity. Liquid fuels. Gears. Glass. Plastics. Digital computers. And yes, transformers.
- pfisherman 1y agoYou would not need much more than 2 megabases. The genome is not one contiguous sequence. It is organized (physically segregated) into chromosomes and topologically associated domains. IIRC 2 megabases is like the 3 sd threshold for interactions between cis regulatory elements / variants and their effector genes.
- eleveriven 1y agoEven just modeling 3D genome organization or ultra-long-range enhancers more realistically could open up new insights