3 ms·
It does remain true, that's the entire point. With GLP-1 you can be more full than without, but that doesn't mean that a baked potato and french fries grant equ
by lanfeust6 1y ago
It does remain true, that's the entire point. With GLP-1 you can be more full than without, but that doesn't mean that a baked potato and french fries grant equivalent satiety! Your body also adapts somewhat to the medication.
If you factor in metabolic adaptation, then re-introduction of surplus calories will lead to regaining weight, even if they weren't as many calories as before.
For the reports of mediated cravings, also: some people don't just overeat from physical cravings, but for emotional satisfaction. A binge session on comfort food has almost nothing to do with hunger. This is something addressed through therapy, not pills.
- SpicyLemonZest 1y agoI wouldn't argue for a strict equivalence, but research shows (https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5073929 https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5073929) that people who go on GLP-1 drugs shift their food habits to decrease consumption of calorie-dense processed foods. It's hard to 100% prove this is causal (or that "calorie-dense processed" means low satiety), but it matches widely reported anecdotes (https://www.nytimes.com/2024/11/19/magazine/ozempic-junk-food.html https://www.nytimes.com/2024/11/19/magazine/ozempic-junk-foo...) that GLP-1s cause hyperpalatable junk food to be unappealing. For me personally, I can't even eat a full slice of cake anymore.
- lanfeust6 1y agoI'd hold out for stronger evidence, because my own anecdotal experience is that those on GLP-1 periodically feel sick but otherwise still seek out the same foods they always had. Also they are very much still capable of binging, on days they don't feel particularly sick.