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There's a niche online health community which follows the work of a late Dr. Ray Peat, who have been touting the benefits of aspirin for a long time: https://r

There's a niche online health community which follows the work of a late Dr. Ray Peat, who have been touting the benefits of aspirin for a long time: https://raypeat.com/articles/aging/aspirin-brain-cancer.shtml https://raypeat.com/articles/aging/aspirin-brain-cancer.shtm... Some of Dr. Peat's disciples have even begun their own independent cancer research (in mice) trying to prove efficacy of far more basic interventions: https://x.com/haidut/status/1751716166387597730 https://x.com/haidut/status/1751716166387597730 I've been an observer of this sphere since ~2017, have implemented various Peat-related concepts towards my own health and fitness, to overall positive results. What's interesting is seeing more and more of these theories - under the theme of 'bioenergetics' - starting to be proven out even in conventional research.

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ufo 2y ago
Ray Peat is as quacky as health quacks can get. Completely nuts.
- runjake 2y ago
  Can you provide some examples that back up your statement? Edit: Some people are getting angry (and in some cases, deleting their comments). Let me be clearer: I have no idea who Ray Peat is. The OP commented that Peat is a "quack" and I was just asking why, because they didn't provide any supporting documentation. Oddly enough, I just now discovered that I used to live down the street from Peat, before he passed away. I don't recall ever meeting him, though.
  - dfxm12 2y ago
    Many appear to be public information. Here are some listed on his RationalWiki entry: Avocados Peat claimed that avocados are carcinogenic because they contain a lot of unsaturated fat.[8] Like all the other nonsense he spouted, he failed to back up this ridiculous claim with any scientific evidence. Orange juice Peat was a big fan of orange juice which he said is "anti-estrogenic".[41] He also claimed that orange juice is good because it raises people's cholesterol.[42] There is not any evidence in the medical literature that shows orange juice consumption raises cholesterol. Studies have found the opposite, as it lows LDL-c and total cholesterol.[43][44] A 2022 review of clinical trials found that orange juice significantly reduces circulating total cholesterol levels.[45] Everything Peat said about foods should be fact-checked because in most cases he was entirely wrong in what he had claimed. https://rationalwiki.org/wiki/Ray_Peat https://rationalwiki.org/wiki/Ray_Peat
    - runjake 2y ago
      Thanks. Great page. For some reason, this one didn't show up for me in the first few pages of Google results.
      - yieldcrv 2y ago
        That’s scary, no shared reality Guess it’s why it takes half the population forever to still be “doing their research”
    - NewUser76312 2y ago
      It's important to actually read sources when it comes to controversial people and topics, rather than trusting some Wiki's summation of something. The Wiki completely misrepresents what Dr. Peat said. "He made many other ridiculous claims such as avocados causing cancer.[8]" https://rationalwiki.org/wiki/Ray_Peat#cite_ref-Vegetables_8-0 https://rationalwiki.org/wiki/Ray_Peat#cite_ref-Vegetables_8... Link [8]: "Vegetables". raypeat.com. Goes to: https://raypeat.com/articles/articles/vegetables.shtml https://raypeat.com/articles/articles/vegetables.shtml The quote in question: "Not all fruits, of course, are perfectly safe--avocados, for example, contain so much unsaturated fat that they can be carcinogenic and hepatotoxic." Note that phrasing "can be", "Not... perfectly safe.". Also btw, did you know that carrots "can be" hepatotoxic (toxic to the liver) because of all the vitamin A? This doesn't mean that carrots are bad, but rather that they shouldn't be an excessively large part of one's daily diet. They are not "perfectly safe". Let's examine how Peat came to this idea based on the research. Remember, the actual claim is that "avocados.. can be carcinogenic and hepatotixic." Not that avocados cause cancer. That is not what he wrote. That wiki article has a clear bias. Anyways, his research for the actual claim: "In Vivo 1998 Nov-Dec;12(6):675-89. Comparative anticancer effects of vaccination and dietary factors on experimentally-induced cancers. ... Experiments in mammary glands cancer showed that a 15% olive-oil diet reduced significantly the tumor incidence caused by 9,10-dimethyl-1,2-benzanthracene. The antitumor effect of the olive-oil diet was connected to its content of monounsaturated fatty acids, such as oleic and palmitic acids. The promotive tumorigenic effects of other high-fat diets (avocado, soybeans) were associated with high content of some polyunsaturated fatty acids (linoleic and alpha-linolenic). Different diets have different targets. The effect of the same diet depends on its anti-tumor substances content. CONCLUSIONS: Vaccination and some diets have similar mechanism in their tumor-preventive effects." "Ann Nutr Metab 1991;35(5):253-60. Effect of dietary avocado oils on hepatic collagen metabolism. Wermam MJ, Mokady S, Neeman I Department of Food Engineering and Biotechnology, Technion - Israel Institute of Technology, Haifa. The effect of various avocado and soybean oils on collagen metabolism in the liver was studied in growing female rats for 8 weeks and in day-old chicks for 1 week. In comparison with rats fed either refined avocado oil, refined or unrefined soybean oils, rats fed unrefined avocado oil showed a significant decrease in total collagen solubility in the liver, while there were no changes in total collagen, protein and moisture content. Chicks fed unrefined avocado oil as compared to those fed refined avocado oil also showed a decrease in hepatic total soluble collagen while hepatic total collagen remained unaffected. Electron micrographs and light-microscope examinations of rats' liver revealed collagen accumulation in the periportal location. This is suggestive of the early stages of fibrosis." All he did was link real-world research to a possible hypothesis. A logical argument. Now you can criticize this argument and say that we can't draw any such conclusions from in vivo and animal model experiments, but at least then you'd be actually engaging with the content of the ideas, not outsourcing your thinking to a poorly-written Wiki article.
  - deleted 2y ago
    [deleted]
cogman10 2y ago
I looked up Ray Peat because I was unfamiliar with him. I'm sure some of his advice has backing to it. A lot of it doesn't. A good amount of it even has a fair body of evidence against the claim (like Alzheimer's can be stopped by using tobacco). This is classic highlighting hits while ignoring misses. A quack that tells you to exercise and eat 5lbs of raw chicken every day can be right about the exercise, that doesn't mean their raw chicken diet is also valid.
- beauzero 2y ago
  "There is some evidence that exposure to nicotine, which is one of the components of cigarette smoke, can actually reduce the risk of dementia. Such reports may be useful in indicating possible research directions for drug design. However, nicotine intake through smoking would not be beneficial. Any positive effects would be outweighed by the significant harm caused by the other toxic components in cigarette smoke." https://www.alzheimers.org.uk/about-dementia/managing-the-risk-of-dementia/reduce-your-risk-of-dementia/smoking#:~:text=There%20is%20some%20evidence%20that,smoking%20would%20not%20be%20beneficial. https://www.alzheimers.org.uk/about-dementia/managing-the-ri...
  - BurningFrog 2y ago
    Nicotine is cheaply available in pill, patch and gum form.
  - b112 2y ago
    However, nicotine intake through smoking would not be beneficial. They are speaking generically of course, if someone was genetically predisposed, or showed other signs, it could make sense.
- giantg2 2y ago
  I mean, I don't care about all of the failed Tesla work, nor his odd life. But I sure do like my transmitted electricity.
  - hombre_fatal 2y ago

deleted 2y ago

[deleted]

ufo 2y ago

Ray Peat is as quacky as health quacks can get. Completely nuts.

runjake 2y ago
Can you provide some examples that back up your statement? Edit: Some people are getting angry (and in some cases, deleting their comments). Let me be clearer: I have no idea who Ray Peat is. The OP commented that Peat is a "quack" and I was just asking why, because they didn't provide any supporting documentation. Oddly enough, I just now discovered that I used to live down the street from Peat, before he passed away. I don't recall ever meeting him, though.
- dfxm12 2y ago
  Many appear to be public information. Here are some listed on his RationalWiki entry: Avocados Peat claimed that avocados are carcinogenic because they contain a lot of unsaturated fat.[8] Like all the other nonsense he spouted, he failed to back up this ridiculous claim with any scientific evidence. Orange juice Peat was a big fan of orange juice which he said is "anti-estrogenic".[41] He also claimed that orange juice is good because it raises people's cholesterol.[42] There is not any evidence in the medical literature that shows orange juice consumption raises cholesterol. Studies have found the opposite, as it lows LDL-c and total cholesterol.[43][44] A 2022 review of clinical trials found that orange juice significantly reduces circulating total cholesterol levels.[45] Everything Peat said about foods should be fact-checked because in most cases he was entirely wrong in what he had claimed. https://rationalwiki.org/wiki/Ray_Peat https://rationalwiki.org/wiki/Ray_Peat
  - runjake 2y ago
    Thanks. Great page. For some reason, this one didn't show up for me in the first few pages of Google results.
    - yieldcrv 2y ago
      That’s scary, no shared reality Guess it’s why it takes half the population forever to still be “doing their research”
  - NewUser76312 2y ago
    It's important to actually read sources when it comes to controversial people and topics, rather than trusting some Wiki's summation of something. The Wiki completely misrepresents what Dr. Peat said. "He made many other ridiculous claims such as avocados causing cancer.[8]" https://rationalwiki.org/wiki/Ray_Peat#cite_ref-Vegetables_8-0 https://rationalwiki.org/wiki/Ray_Peat#cite_ref-Vegetables_8... Link [8]: "Vegetables". raypeat.com. Goes to: https://raypeat.com/articles/articles/vegetables.shtml https://raypeat.com/articles/articles/vegetables.shtml The quote in question: "Not all fruits, of course, are perfectly safe--avocados, for example, contain so much unsaturated fat that they can be carcinogenic and hepatotoxic." Note that phrasing "can be", "Not... perfectly safe.". Also btw, did you know that carrots "can be" hepatotoxic (toxic to the liver) because of all the vitamin A? This doesn't mean that carrots are bad, but rather that they shouldn't be an excessively large part of one's daily diet. They are not "perfectly safe". Let's examine how Peat came to this idea based on the research. Remember, the actual claim is that "avocados.. can be carcinogenic and hepatotixic." Not that avocados cause cancer. That is not what he wrote. That wiki article has a clear bias. Anyways, his research for the actual claim: "In Vivo 1998 Nov-Dec;12(6):675-89. Comparative anticancer effects of vaccination and dietary factors on experimentally-induced cancers. ... Experiments in mammary glands cancer showed that a 15% olive-oil diet reduced significantly the tumor incidence caused by 9,10-dimethyl-1,2-benzanthracene. The antitumor effect of the olive-oil diet was connected to its content of monounsaturated fatty acids, such as oleic and palmitic acids. The promotive tumorigenic effects of other high-fat diets (avocado, soybeans) were associated with high content of some polyunsaturated fatty acids (linoleic and alpha-linolenic). Different diets have different targets. The effect of the same diet depends on its anti-tumor substances content. CONCLUSIONS: Vaccination and some diets have similar mechanism in their tumor-preventive effects." "Ann Nutr Metab 1991;35(5):253-60. Effect of dietary avocado oils on hepatic collagen metabolism. Wermam MJ, Mokady S, Neeman I Department of Food Engineering and Biotechnology, Technion - Israel Institute of Technology, Haifa. The effect of various avocado and soybean oils on collagen metabolism in the liver was studied in growing female rats for 8 weeks and in day-old chicks for 1 week. In comparison with rats fed either refined avocado oil, refined or unrefined soybean oils, rats fed unrefined avocado oil showed a significant decrease in total collagen solubility in the liver, while there were no changes in total collagen, protein and moisture content. Chicks fed unrefined avocado oil as compared to those fed refined avocado oil also showed a decrease in hepatic total soluble collagen while hepatic total collagen remained unaffected. Electron micrographs and light-microscope examinations of rats' liver revealed collagen accumulation in the periportal location. This is suggestive of the early stages of fibrosis." All he did was link real-world research to a possible hypothesis. A logical argument. Now you can criticize this argument and say that we can't draw any such conclusions from in vivo and animal model experiments, but at least then you'd be actually engaging with the content of the ideas, not outsourcing your thinking to a poorly-written Wiki article.
- deleted 2y ago
  [deleted]

cogman10 2y ago

I looked up Ray Peat because I was unfamiliar with him. I'm sure some of his advice has backing to it. A lot of it doesn't. A good amount of it even has a fair body of evidence against the claim (like Alzheimer's can be stopped by using tobacco). This is classic highlighting hits while ignoring misses. A quack that tells you to exercise and eat 5lbs of raw chicken every day can be right about the exercise, that doesn't mean their raw chicken diet is also valid.

beauzero 2y ago
"There is some evidence that exposure to nicotine, which is one of the components of cigarette smoke, can actually reduce the risk of dementia. Such reports may be useful in indicating possible research directions for drug design. However, nicotine intake through smoking would not be beneficial. Any positive effects would be outweighed by the significant harm caused by the other toxic components in cigarette smoke." https://www.alzheimers.org.uk/about-dementia/managing-the-risk-of-dementia/reduce-your-risk-of-dementia/smoking#:~:text=There%20is%20some%20evidence%20that,smoking%20would%20not%20be%20beneficial. https://www.alzheimers.org.uk/about-dementia/managing-the-ri...
- BurningFrog 2y ago
  Nicotine is cheaply available in pill, patch and gum form.
- b112 2y ago
  However, nicotine intake through smoking would not be beneficial. They are speaking generically of course, if someone was genetically predisposed, or showed other signs, it could make sense.
giantg2 2y ago
I mean, I don't care about all of the failed Tesla work, nor his odd life. But I sure do like my transmitted electricity.
- hombre_fatal 2y ago