2 ms·

They really didn't solve it. AF works great for proteins that have a homologous protein with a crystal structure. It is absolutely useless for proteins with no

They really didn't solve it. AF works great for proteins that have a homologous protein with a crystal structure. It is absolutely useless for proteins with no published structure to use as a template - e.g. many of the undrugged cancer targets in existence.

dekhn 2y ago
that's not true (I work in the field) but it's not an interesting argument to have.
shpongled 2y ago
@dekhn it is true (I also work in the field. I'm a software engineer who got a wet-lab PhD in biochemistry and work at a biotech doing oncology drug discovery)