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Celiac is a very clear cut medical condition. Most gluten intolerance seems to be nothing but hypochondria, with along with your standard "restrictive diets wor

by wisty 2y ago

Celiac is a very clear cut medical condition. Most gluten intolerance seems to be nothing but hypochondria, with along with your standard "restrictive diets work until people figure out how to eat highly processed garbage with the new restriction" effect.

BigGreenJorts 2y ago
Seconding the fact the celiac is it's own condition, but gluten is something that seems to be a culprit of IBS symptoms in certain people. That doesn't mean that gluten is bad, just that it causes a poor reaction in some people. Avocados are another one of these things. Some doctors like to call these "digestive allergies" to give patients an idea of how they can vary in severity and that they're for all intents and purposes a misdiagnosis from the immune system.
- CharlieDigital 2y ago
  > ...gluten is something that seems to be a culprit of IBS symptoms in certain people. That doesn't mean that gluten is bad, just that it causes a poor reaction in some people... This is also my take on it. I've watched it first hand with my wife -- who is 1/2 Italian -- giving up pasta and bread in the last few years. It has made a huge difference in her daily quality of life with respect to digestive issues (mainly bloating and gassiness). Gluten is a protein so it's not hard to imagine that either this protein is not easily digested by some folks or some byproduct of its digestion feeds some specific gut bacteria that produces inflammatory compounds. If Celiac is a full blown immune response to inflammation caused by gluten, then it seems reasonable that some folks would have a spectrum of reactions to barely registering it or somewhere in between (like my wife). It's possible that it's some other compound that's prevalent in wheat, but avoiding wheat-based products has been life changing for my wife. I would add that this has developed with age similarly to how she has become lactose intolerant as well around the time she turned 40 so if you're in your 20's or 30's and you think this is malarkey, well, give it time (and really enjoy your lactose and gluten!). Why folks downvoted the original comment, I don't understand; this is based on firsthand experience hacking her diet and observing how she felt. I'm not here on some anti-gluten crusade (my kids eat and enjoy plenty of gluten for the entire household!)
  - Beijinger 2y ago
    "well, give it time (and really enjoy your lactose and gluten!)." And don't forget to avoid Glyphosate :-)
  - tstrimple 2y ago
    This describes my wife almost exactly. Developed gluten and lactose intolerance right around 40. She was one of those people who had to have at least one glass of milk a day and a gallon of ice cream a week and that had to be cut out 100%. She reacts to very small amounts of milk and gluten products. Even top ramen flavor packets in a pasta salad contain enough wheat and milk to give her a miserable day. Much like HFCS, dairy and wheat are fillers in SO many products that it's become a chore to shop and almost impossible to eat out spontaneously anymore.
    - CharlieDigital 2y ago
      > This describes my wife almost exactly. Developed gluten and lactose intolerance right around 40. Anecdotally, I've heard this from other women in my wife's peer group so I also wonder if some of this is related to hormonal changes from child birth or maybe even pre-menopause. Her reactions are not as severe as your spouse's -- just gasiness and general abdominal discomfort (enough that it's not worth it for the satisfaction of eating pasta and dairy day-to-day). She will still occasionally indulge. I, for one, still happily consume gluten and lactose (to her chagrin) despite being Asian.
      - ikr678 2y ago
        I think the high level theory is that women have stronger immune systems/immune responses (protective evolution for childbirth) so foods that cause inflamation or gut irritation result in a disproportionate reaction.
- deleted 2y ago
  [deleted]
imtringued 2y ago
I'm not sure what you mean by "clear cut medical condition" other than that it is easy to test.
- Beijinger 2y ago
  ROTFL. How? Enzyme test? There are three different ones. All of them are unreliable, hence normally doctors do all of them at once. Gene test? Trying to avoid gluten? Don't forget, first you have to suspect to have a gluten problem. There are many forms of celiac. And there are forms that are unlikely to be diagnosed by a doctor. They may even not know what you have if you tell them the name of the disease and have to google it.
  - petercooper 2y ago
    And in many cases it's also necessary to provoke the problem in order to test properly. I've been on a gluten free diet for ten years (my skin kept falling off, stopped when I quit gluten, father had celiac) and always test negative because I won't gorge on gluten for the two weeks necessary for antibodies to show up (simply as I don't have a month spare to be ill).
Beijinger 2y ago
"Celiac is a very clear cut medical condition." No, it is not. It comes in a bunch of varieties and there is news: https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ "Most gluten intolerance seems to be nothing but hypochondria" Well, tell this to somebody who nearly died of it. First diagnosis when I walked into the hospital: HIV in the final stage! But I have a super rare form of it. Incidence 1:100000
- gruez 2y ago
  >No, it is not. It comes in a bunch of varieties and there is news: https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ From the abstract >Fish exposed to glyphosate develop digestive problems that are reminiscent of celiac disease The rest seems to be theorizing with no empirical evidence
  - Beijinger 2y ago
    The is no proof (there is never proof in science) but there is reason to be suspicious. https://pmc.ncbi.nlm.nih.gov/articles/PMC7545723/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7545723/ Glyphosate exposure, either through active ingredient alone or commercial herbicide formulations, has the potential to induce dysbiosis by creating an imbalance between commensal members of the gastrointestinal microbiome and opportunistic pathogens. Glyphosate may be a critical environmental trigger in the etiology of several disease states associated with dysbiosis, including celiac disease, inflammatory bowel disease and irritable bowel syndrome. Glyphosate exposure may also have consequences for mental health, including anxiety and depression, through alterations in the gut microbiome. However, the research surrounding glyphosate’s effects on the gut microbiome also suffers from numerous methodological weaknesses including artificially high-doses, insufficient duration, proprietary ingredients and an over reliance on animal models. Future long-term studies examining physiologically relevant doses in both healthy and genetically susceptible populations are warranted to determine the real risk posed to human health.
    - deleted 2y ago
      [deleted]

by wisty 2y ago

BigGreenJorts 2y ago

Seconding the fact the celiac is it's own condition, but gluten is something that seems to be a culprit of IBS symptoms in certain people. That doesn't mean that gluten is bad, just that it causes a poor reaction in some people. Avocados are another one of these things. Some doctors like to call these "digestive allergies" to give patients an idea of how they can vary in severity and that they're for all intents and purposes a misdiagnosis from the immune system.

CharlieDigital 2y ago
> ...gluten is something that seems to be a culprit of IBS symptoms in certain people. That doesn't mean that gluten is bad, just that it causes a poor reaction in some people... This is also my take on it. I've watched it first hand with my wife -- who is 1/2 Italian -- giving up pasta and bread in the last few years. It has made a huge difference in her daily quality of life with respect to digestive issues (mainly bloating and gassiness). Gluten is a protein so it's not hard to imagine that either this protein is not easily digested by some folks or some byproduct of its digestion feeds some specific gut bacteria that produces inflammatory compounds. If Celiac is a full blown immune response to inflammation caused by gluten, then it seems reasonable that some folks would have a spectrum of reactions to barely registering it or somewhere in between (like my wife). It's possible that it's some other compound that's prevalent in wheat, but avoiding wheat-based products has been life changing for my wife. I would add that this has developed with age similarly to how she has become lactose intolerant as well around the time she turned 40 so if you're in your 20's or 30's and you think this is malarkey, well, give it time (and really enjoy your lactose and gluten!). Why folks downvoted the original comment, I don't understand; this is based on firsthand experience hacking her diet and observing how she felt. I'm not here on some anti-gluten crusade (my kids eat and enjoy plenty of gluten for the entire household!)
- Beijinger 2y ago
  "well, give it time (and really enjoy your lactose and gluten!)." And don't forget to avoid Glyphosate :-)
- tstrimple 2y ago
  This describes my wife almost exactly. Developed gluten and lactose intolerance right around 40. She was one of those people who had to have at least one glass of milk a day and a gallon of ice cream a week and that had to be cut out 100%. She reacts to very small amounts of milk and gluten products. Even top ramen flavor packets in a pasta salad contain enough wheat and milk to give her a miserable day. Much like HFCS, dairy and wheat are fillers in SO many products that it's become a chore to shop and almost impossible to eat out spontaneously anymore.
  - CharlieDigital 2y ago
    > This describes my wife almost exactly. Developed gluten and lactose intolerance right around 40. Anecdotally, I've heard this from other women in my wife's peer group so I also wonder if some of this is related to hormonal changes from child birth or maybe even pre-menopause. Her reactions are not as severe as your spouse's -- just gasiness and general abdominal discomfort (enough that it's not worth it for the satisfaction of eating pasta and dairy day-to-day). She will still occasionally indulge. I, for one, still happily consume gluten and lactose (to her chagrin) despite being Asian.
    - ikr678 2y ago
      I think the high level theory is that women have stronger immune systems/immune responses (protective evolution for childbirth) so foods that cause inflamation or gut irritation result in a disproportionate reaction.
deleted 2y ago
[deleted]

imtringued 2y ago

I'm not sure what you mean by "clear cut medical condition" other than that it is easy to test.

Beijinger 2y ago
ROTFL. How? Enzyme test? There are three different ones. All of them are unreliable, hence normally doctors do all of them at once. Gene test? Trying to avoid gluten? Don't forget, first you have to suspect to have a gluten problem. There are many forms of celiac. And there are forms that are unlikely to be diagnosed by a doctor. They may even not know what you have if you tell them the name of the disease and have to google it.
- petercooper 2y ago
  And in many cases it's also necessary to provoke the problem in order to test properly. I've been on a gluten free diet for ten years (my skin kept falling off, stopped when I quit gluten, father had celiac) and always test negative because I won't gorge on gluten for the two weeks necessary for antibodies to show up (simply as I don't have a month spare to be ill).

Beijinger 2y ago

"Celiac is a very clear cut medical condition." No, it is not. It comes in a bunch of varieties and there is news: https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ "Most gluten intolerance seems to be nothing but hypochondria" Well, tell this to somebody who nearly died of it. First diagnosis when I walked into the hospital: HIV in the final stage! But I have a super rare form of it. Incidence 1:100000

gruez 2y ago
>No, it is not. It comes in a bunch of varieties and there is news: https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3945755/ From the abstract >Fish exposed to glyphosate develop digestive problems that are reminiscent of celiac disease The rest seems to be theorizing with no empirical evidence
- Beijinger 2y ago
  The is no proof (there is never proof in science) but there is reason to be suspicious. https://pmc.ncbi.nlm.nih.gov/articles/PMC7545723/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7545723/ Glyphosate exposure, either through active ingredient alone or commercial herbicide formulations, has the potential to induce dysbiosis by creating an imbalance between commensal members of the gastrointestinal microbiome and opportunistic pathogens. Glyphosate may be a critical environmental trigger in the etiology of several disease states associated with dysbiosis, including celiac disease, inflammatory bowel disease and irritable bowel syndrome. Glyphosate exposure may also have consequences for mental health, including anxiety and depression, through alterations in the gut microbiome. However, the research surrounding glyphosate’s effects on the gut microbiome also suffers from numerous methodological weaknesses including artificially high-doses, insufficient duration, proprietary ingredients and an over reliance on animal models. Future long-term studies examining physiologically relevant doses in both healthy and genetically susceptible populations are warranted to determine the real risk posed to human health.
  - deleted 2y ago
    [deleted]