4 ms·

Often you’re not allowed on your medication for any of your other health issues.

• londons_explore 2y ago
  We need a new approach to randomly controlled trials. I propose a new approach: Rather than given treatment vs not given treatment, we instead vary the dose slightly, and we include the whole world in the trial. Ie. instead of taking 100mg of Advil, instead you will receive somewhere between 95mg and 105mg of Advil. You won't be told how much you got - but the barcode on the box will encode that info. That already might be the case due to allowed inaccuracies, but now we're gonna measure and record it. Later, the data of which box was dispensed is combined with any other relevant medical records, and across the hundreds of millions of people involved, any benefit/disadvantage of a small increase or decrease in dose will become apparent.
  • refulgentis 2y ago
    This doesn't sound very helpful
    • advael 2y ago
      I mean it sounds like a way to trick people into letting a giant company build a surveillance system, and I imagine aliens observing humans in this moment in history might conclude that's what we want, but for science or the benefit of the people "surveyed" it's mostly downsides
  • malfist 2y ago
    That's not generally how drugs work. There's wide margins on how much dose is required for clinically significant results. Not only is the 110 pouns petite woman taking the same dose of aspirin as a 400lb elite powerlifter, but the effects can't be quantified in high resolution. The woman can't say her pain was 5% less than the powerlifter, and they can't say their pain was 5% more.