3 ms·

There were several side effects related to pancreatic cancer associated with the precursors to GLP-1 drugs. The same companies promoting GLP-1s were responsible

by sss111 2y ago

There were several side effects related to pancreatic cancer associated with the precursors to GLP-1 drugs. The same companies promoting GLP-1s were responsible for driving up insulin prices. So I'm hedging my bets. There's a really cool Modern MBA video [1] on this topic btw :) [1]: https://www.youtube.com/watch?v=7sUoZVke_30 https://www.youtube.com/watch?v=7sUoZVke_30

cyberax 2y ago
> There were several side effects related to pancreatic cancer In mice.
- copperx 2y ago
  Did the drug help pancreatic cancer?
- minifridge 2y ago
  If something causes cancer in mice, the curent consensus is that it is deemed unsafe for humans.
  - cyberax 2y ago
    Not really. Mice are naturally genetically pre-disposed to cancer. So in general, if something _doesn't_ cause cancer in mice, then it's probably safe for humans. The reverse is not necessarily true. Also, GLP-1 was associated with thyroid, not pancreatic cancer.
    - deleted 2y ago
      [deleted]
- akira2501 2y ago
  Were they humanized mice or not?
- the__alchemist 2y ago
  This is a good example of a thought-terminating cliche.
  - sss111 2y ago
    nice, learned something new today, people use this so often
  - cyberax 2y ago
    There used to be a Twitter bot that replied "in mice" to all breathless tweets reporting on various studies.
pixl97 2y ago
>Large epidemiological studies have shown the link between obesity and pancreatic cancer. A large population-based case-control study of pancreatic cancer demonstrated that obesity was associated with a statistically significant 50–60% increased risk of pancreatic cancer. So does obesity, so there is that.