4 ms·

The Worst Argument Against Ozempic

1 points by NavinF 2y ago

NavinF 2y ago
>The argument is that GLP-1s are bad… because you regain weight when you stop them? By the same logic, diet and exercise are bad because, when you cut them out, you’ll also tend to regain weight Amusingly enough, I've heard the same silly argument used against creatine. "If you stop taking it, you won't be stronger anymore"
obpe 2y ago
The reason it's a problem is the cost. Diet and exercise are free.
- baanist 2y ago
  It's easier to take drugs even if it costs a lot of money.
- NavinF 2y ago
  Are you looking at the fake retail price or the actual price? See https://www.astralcodexten.com/p/the-compounding-loophole https://www.astralcodexten.com/p/the-compounding-loophole The median american has a >62k disposable income and can easily afford to pay $254/month to a compounding pharmacy (not covered by insurance) https://en.wikipedia.org/wiki/Disposable_household_and_per_capita_income#Disposable_income_per_capita_(OECD) https://en.wikipedia.org/wiki/Disposable_household_and_per_c...
  - clipsy 2y ago
    > The median american has a >62k disposable income and can easily afford to pay $254/month to a compounding pharmacy (not covered by insurance) The median US American household has an income (pre-tax) of $80,610 as of 2023[0]; the idea that that translates into $62k of disposable income simply does not pass the smell test. I suspect the various adjustments[1] described in your source are deeply misrepresenting reality. [0]: https://www.census.gov/newsroom/press-releases/2024/income-poverty-health-insurance-coverage.html https://www.census.gov/newsroom/press-releases/2024/income-p... [1]: "This indicator also takes account of social transfers in kind 'such as health or education provided for free or at reduced prices by governments and not-for-profit organisations.' The data shown below is published by the OECD and is presented in purchasing power parity (PPP) in order to adjust for price differences between countries."
  - obpe 2y ago
    The poorer you are the more likely you are to be obese.
    - NavinF 2y ago
      Sure but I stand by my statement. The vast majority of Americans can afford $254/month. Prices will go down with competition and crash when the FDA Exclusivity period expires
glp1guide 2y ago
Super tired of seeing this argument. Most people who get on GLP1 Receptor Agonists keep their weight gains. If someone told you there was a consistent, well researched and studied way to lose 5% of your body weight, would you take it? Of course. Also, not to mention that the period of time where you're experiencing better HbA1c, etc can be a lifeline. https://glp1.guide/content/do-people-regain-all-the-weight-lost-on-glp1-receptor-agonists https://glp1.guide/content/do-people-regain-all-the-weight-l... GLP-1s aren't con-free, but this ain't it.

1 points by NavinF 2y ago

>The argument is that GLP-1s are bad… because you regain weight when you stop them? By the same logic, diet and exercise are bad because, when you cut them out, you’ll also tend to regain weight Amusingly enough, I've heard the same silly argument used against creatine. "If you stop taking it, you won't be stronger anymore"

obpe 2y ago

The reason it's a problem is the cost. Diet and exercise are free.

baanist 2y ago
It's easier to take drugs even if it costs a lot of money.
NavinF 2y ago
Are you looking at the fake retail price or the actual price? See https://www.astralcodexten.com/p/the-compounding-loophole https://www.astralcodexten.com/p/the-compounding-loophole The median american has a >62k disposable income and can easily afford to pay $254/month to a compounding pharmacy (not covered by insurance) https://en.wikipedia.org/wiki/Disposable_household_and_per_capita_income#Disposable_income_per_capita_(OECD) https://en.wikipedia.org/wiki/Disposable_household_and_per_c...
- clipsy 2y ago
  > The median american has a >62k disposable income and can easily afford to pay $254/month to a compounding pharmacy (not covered by insurance) The median US American household has an income (pre-tax) of $80,610 as of 2023[0]; the idea that that translates into $62k of disposable income simply does not pass the smell test. I suspect the various adjustments[1] described in your source are deeply misrepresenting reality. [0]: https://www.census.gov/newsroom/press-releases/2024/income-poverty-health-insurance-coverage.html https://www.census.gov/newsroom/press-releases/2024/income-p... [1]: "This indicator also takes account of social transfers in kind 'such as health or education provided for free or at reduced prices by governments and not-for-profit organisations.' The data shown below is published by the OECD and is presented in purchasing power parity (PPP) in order to adjust for price differences between countries."
- obpe 2y ago
  The poorer you are the more likely you are to be obese.
  - NavinF 2y ago
    Sure but I stand by my statement. The vast majority of Americans can afford $254/month. Prices will go down with competition and crash when the FDA Exclusivity period expires

glp1guide 2y ago

Super tired of seeing this argument. Most people who get on GLP1 Receptor Agonists keep their weight gains. If someone told you there was a consistent, well researched and studied way to lose 5% of your body weight, would you take it? Of course. Also, not to mention that the period of time where you're experiencing better HbA1c, etc can be a lifeline. https://glp1.guide/content/do-people-regain-all-the-weight-lost-on-glp1-receptor-agonists https://glp1.guide/content/do-people-regain-all-the-weight-l... GLP-1s aren't con-free, but this ain't it.