4 ms·
It's pretty awkward to talk about making people form a lifelong addiction to one drug (semaglutide) to counteract the effects of making people form a lifelong a
by readthenotes1 2y ago
It's pretty awkward to talk about making people form a lifelong addiction to one drug (semaglutide) to counteract the effects of making people form a lifelong addiction to a poison (sugar).
If we spent half the money involved in this scam in removing added sugar from the grocery store shelves we'd beat that epidemic (don't believe me? Look at pictures of people living before the low-fat high carb poisoning in the 80s and 90s)
- Zelphyr 2y agoI would add ultra-processed foods to this as well. I firmly believe that, decades from now, we will look back in horror at what food manufacturers have done to us.
- diffeomorphism 2y agoWhy is this an "instead"? We already know that people on semaglutides buy less junk food because to them it is less addictive. Less demand, less supply. If anything, this seems like a useful way to smooth the transition to less unhealthy food supply.
- alamortsubite 2y agoPeople are effectively on these medications permanently or they regain whatever weight they lost on them. So unfortunately the transition isn't so much to healthier diets, but to taking weight-loss drugs forever.
- orwin 2y agoIs this true? Is the rebound effect as high as you think? Because I know 2 people who took it for like 3 years, and while they took some weight back, they're not obese anymore.
- alamortsubite 2y agoNot according to Novo Nordisk. https://www.bbc.com/future/article/20240521-what-happens-when-you-stop-taking-ozempic https://www.bbc.com/future/article/20240521-what-happens-whe... The same trend was seen after the 2021 trial, known as Step 1. After 68 weeks of semaglutide injections, the average patient lost more than 15% of their body weight, but within 12 months of treatment ending, patients regained two thirds of their prior weight loss on average. This was associated with a similar level of reversion to the patients' original baselines in some markers of their cardiometabolic health – a category which includes conditions such as diabetes and heart attacks. Both Rubino and other experts around the world have seen similar patterns when administering GLP-1 drugs in their clinics. "There will be a small proportion of people, 10% maximum, that are able to maintain [all] the weight they've lost," says Alex Miras, a clinical professor of medicine at Ulster University.
- orwin 2y ago2/3 of the weight back seems high to me, but the people I know also retired during their treatment, maybe some cofunding factors exist.
- diffeomorphism 2y agoSo even with rebound they lost more than 5% of their body weight long term. Seems good.
- consteval 2y agoTo be fair, semaglutide also lowers addiction to nicotine and alcohol, and maybe other drugs. It seems to me some people have a broken reward system and some... don't. Some people can live life without ever seeking out a vice, and some people are unable to live without a vice. Probably, from an evolutionary perspective, this made sense. But when you have a surplus of addictive things like sugar, nicotine, and alcohol, combined with mass society-wide manipulation to indulge via advertisement... well this functionality of the human brain makes less sense.
- tpush 2y agoNeither is sugar a poison nor the general driver of the obesity epidemic.