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Regular Glucosamine Use and Mortality
- Khelavaster 2y agoWhat if everyone got enough glycine while their blood sugar was adequate, so that their glucosamine levels topped up...
- zingababba 2y agoSupplemental glycine instantly gives me crippling insomnia. Even magnesium glycinate or anything else bound to it causes issues.
- OutOfHere 2y agoCollagen hydrolysate is a better source for getting the benefits of glycine than is pure glycine.
- Khelavaster 2y agoglycine needs to be taken with lysine and vitamin C to keep from depleting lysine into collagen..
- zingababba 2y agoInteresting, thanks.
- vjerancrnjak 2y agoInteresting preliminary investigation but there’s no mathematics that can remove confounding factors for such small effects.
- drxzcl 2y agoIt’s 500k people for over a decade. If any study has the data to do it, it’s this one.
- zihotki 2y agoIt's an observational study. You can't make conclusions based on it. But it can be a basis for more detailed study.
- LorenPechtel 2y agoSample size is useless at removing confounders.
- LeoPanthera 2y agoFor me this URL leads to a Wordpress login page.
- zihotki 2y agoFrom the article: >> regular glucosamine use may be a marker for a healthy lifestyle, but it is hard to distinguish the confounding effects of a healthy lifestyle from the impact of regular supplementations in an observational study.
- deleted 2y ago[deleted]
- LorenPechtel 2y agoYeah, everything about such longevity studies has such obvious confounders that it seems pretty much useless.
- chaostheory 2y agoIt might enable you to have a healthier lifestyle since it helps with mobility.
- anon1358 2y ago[dead]
- amelius 2y ago> The inverse associations of glucosamine use with all-cause mortality seemed to be somewhat stronger among current than non-current smokers So take glucosamine and start smoking? /s
- deleted 2y ago[deleted]
- beefman 2y ago(2020)
- cryptichash 2y agoBased on a quick survey [1], seems like various forms of glucosamine are not interchangeable. Doesn't this confound the study further given its unclear which supplements led to what outcomes? [1] https://www.mayoclinic.org/drugs-supplements-glucosamine/art-20362874 https://www.mayoclinic.org/drugs-supplements-glucosamine/art...
- dave333 2y agoGlucosamine seems to be taken to treat joint pain and osteoarthritis but would a general anti-inflammatory effect be what causes a reduction in mortality if any?
- ImHereToVote 2y agoIsn't Glucosamine needed for Hyaluronic Acid synthesis. Hyaluronic Acid essentially keeps tissues moisturized.
- OutOfHere 2y agoGlucosamine and independently chondroitin can provoke a slight allergic reaction. That's because they're often sea derived. Perhaps lab synthesized versions wouldn't have this issue. The reaction, although not serious, can be enough to discourage their use.
- anon1358 2y ago[dead]
- WalterSear 2y agoThis is from 2020.