6 ms·

That's terrifying. I took a drug once called 3-MMC that I really enjoyed. I haven't been able to find it since and I don't even know a street name. But by all

That's terrifying. I took a drug once called 3-MMC that I really enjoyed. I haven't been able to find it since and I don't even know a street name. But by all accounts it was a pleasant high somewhere between cocaine and MDMA with a moderate duration and minimal comedown. But for all I know it could cause irreparable brain damage. I guess it's not too likely, since most recreational drugs have been around a long time and are well-studied, and most derivatives aren't radically different than their mainstream counterparts. And most street drugs are either prescribed medically or being studied for medical use. The real problem is purity, which is a problem caused by the ineffective and insanely expensive US "ban" on drugs. Solve the purity and regulation issue and you end most overdose deaths, most black market violent crime, and, apparently, accidental brain damage.

morkalork 2y ago
Taking mephedrone analogues bought off the internet in the 2010s was a real wild west and gamble. There's nothing like reading a review from another buyer about how what they ordered has destroyed their brain beyond repair and becoming paranoid its too late, you've done the same to yourself. Thankfully, for me at least, it was probably some drug induced psychosis on their end. Edit: Does anyone remember a Sky News (or other UK) clip where the journalist bought a kilo of mephedrone online from China and received it? I'd love to find it again. It was definitely the moment when the whole scene jumped the shark into absurdity.
- deleted 2y ago
  [deleted]
- vasco 2y ago
  Not to be fear mongering but I knew someone who's boyfriend ordered drugs online like this frequently. They lived together and one morning my girlfriend got a call from a friend, saying the guy killed his girlfriend, walked up and down his apartment building for hours during the night while shouting, and finally killed himself at dawn. No history of any mental illness, completely out of the blue. Surprise pills can definitely be a surprise I guess.
  - brobdingnag_pp 2y ago
    ”Pills” is a misnomer here, we’re talking miniscule doses of powders/liquids. Sounds like they took too much MDPV.
    - herbst 2y ago
      This. MDPV was super available and super super weird. I remember forcing friends to get sleep after days because they reached a literal zombie state. However at least in my circles nothing really bad ever happened
      - Scoundreller 2y ago
        I live in a country that doesn’t update their drug laws very often, but they still went out of their way to schedule mdpv. Was interesting to see that they weren’t entirely asleep at the switch.
    - code_biologist 2y ago
      Minuscule indeed. In the late 2000s I ordered a gram of desoxypipradrol [1] from a sketchy Chinese chemical company. A gram was the smallest unit they'd sell. When it arrived we dissolved it in water at 1mg/mL so we could volumetrically measure 2mg doses accurately. Our first test doses were 500ug. It took us so long to get though the jar that some mold started to grow on the solution, even though we kept it in the fridge! Not wanting to throw hundreds of doses down the drain we scooped off the mold, added Everclear (ethanol), redid our concentration math, and moved the jar to the freezer. Wild, innocent times. Sadly, one of my friends in on the desoxypipradrol jar died from fentanyl contaminated dark web drugs a couple years ago. [1] https://en.wikipedia.org/wiki/Desoxypipradrol https://en.wikipedia.org/wiki/Desoxypipradrol
      - henryaj 2y ago
        That stuff looks fucking terrifying. Incredibly potent and super lipophilic so long-acting...
pprotas 2y ago
Be careful with 3-MMC. It’s rampant in The Netherlands, everyone and their mom is using it as a party drug. 16 year old kids are getting addicted and I have multiple friends that went to rehab for it. Pretty sure I damaged my kidney with it as well.
jamil7 2y ago
3-MMC is huge in Europe at the moment, never tried it but would be a little wary of it as I haven’t found a lot of reliable information on it.
- nirse 2y ago
  This should be a reliable source on 3mmc, but it is in Dutch: https://www.trimbos.nl/aanbod/webwinkel/af1916-factsheet-3mmc/ https://www.trimbos.nl/aanbod/webwinkel/af1916-factsheet-3mm...
  - jamil7 2y ago
    Thanks
- stampedbox 2y ago
  https://www.erowid.org/experiences/subs/exp_3Methylmethcathinone.shtml https://www.erowid.org/experiences/subs/exp_3Methylmethcathi... and it's related chemical https://www.erowid.org/chemicals/4_methylmethcathinone/4_methylmethcathinone.shtml https://www.erowid.org/chemicals/4_methylmethcathinone/4_met...
otherme123 2y ago
Careful! Analogs can be very different in toxicity and other properties: some people drink ethanol on a daily basis, and damage is relatively low. Methanol is similar, but is very toxic and can damage and kill you easily. R-Thalidomide is used as anti-inflamatory and sedative, L-Thalidomide is teratogenic; and what is worse, one form can switch into the other form. The difference between Morphine and Codeine is minimal: a H is changed to a CH3. But one is 10x stronger than the other. In fact, morphine is more similar to codeine than to heroin. There is another opioid called Oripavine, similar to morphine (and can be transformed easily into), that is known to also have analgesic effects, but can't be used because it's highly toxic. It can itself be derived to M320, which is around 10000x more potent than morphine. In the opioid large family we could do this all day, with analogs and very similar molecules having a wild range of potency and toxicity. Don't use similarity between derivatives as a guide or a scale of their potential toxicity. I agree that the easiest and safest way to deal with this is to just legalize all drugs. IMO that will have at least two desirable effects: you will know exactly what you are consuming instead of betting on a derivative, and the race after analogs will stop: people will just consume what is known to be safe and effective, as it happens with alcohol.
- dusted 2y ago
  Funny thing with codine is that it's metabolized into morphine, and this happens at vastly different rates, from "not effective as a treatment" to "somewhat high risk of abuse due to euphoria"
- LoganDark 2y ago
  > I agree that the easiest and safest way to deal with this is to just legalize all drugs. IMO that will have at least two desirable effects: you will know exactly what you are consuming instead of betting on a derivative, and the race after analogs will stop: people will just consume what is known to be safe and effective, as it happens with alcohol. Amen. I'll be happy once I can pick up, say, LSD, from a pharmacy, and know that it's dosed accurately and unadulterated. Right now one would kinda have to buy it from either some guy or some darknet vendor and the only way to know it's safe is to test it with reagents. Those who don't test it run the risk of dying or suffering permanent damage from overdosing on some adulterant or substitute. It would probably also help with the current opioid crisis where people are dying because their doses are adulterated with fentanyl. Just offer doses that don't have fentanyl in it! Let people buy it from a safe regulated source.
pantalaimon 2y ago
Unfortunately a lot of 3-MMC sold these days is actually 3-CMC which is thought to be a lot more neurotoxic.
walthamstow 2y ago
4-MMC for £10 a gram in 2010, bought and sold legally, those were the days. God, it really stunk though.
stampedbox 2y ago
[dead]
jzemeocala 2y ago
I don't know if 3-mmc ever got a street name but it's got a sister compound 4-mmc that's commonly called mephedrone
deleted 2y ago
[deleted]

morkalork 2y ago

Taking mephedrone analogues bought off the internet in the 2010s was a real wild west and gamble. There's nothing like reading a review from another buyer about how what they ordered has destroyed their brain beyond repair and becoming paranoid its too late, you've done the same to yourself. Thankfully, for me at least, it was probably some drug induced psychosis on their end. Edit: Does anyone remember a Sky News (or other UK) clip where the journalist bought a kilo of mephedrone online from China and received it? I'd love to find it again. It was definitely the moment when the whole scene jumped the shark into absurdity.

deleted 2y ago
[deleted]
vasco 2y ago
Not to be fear mongering but I knew someone who's boyfriend ordered drugs online like this frequently. They lived together and one morning my girlfriend got a call from a friend, saying the guy killed his girlfriend, walked up and down his apartment building for hours during the night while shouting, and finally killed himself at dawn. No history of any mental illness, completely out of the blue. Surprise pills can definitely be a surprise I guess.
- brobdingnag_pp 2y ago
  ”Pills” is a misnomer here, we’re talking miniscule doses of powders/liquids. Sounds like they took too much MDPV.
  - herbst 2y ago
    This. MDPV was super available and super super weird. I remember forcing friends to get sleep after days because they reached a literal zombie state. However at least in my circles nothing really bad ever happened
    - Scoundreller 2y ago
      I live in a country that doesn’t update their drug laws very often, but they still went out of their way to schedule mdpv. Was interesting to see that they weren’t entirely asleep at the switch.
  - code_biologist 2y ago
    Minuscule indeed. In the late 2000s I ordered a gram of desoxypipradrol [1] from a sketchy Chinese chemical company. A gram was the smallest unit they'd sell. When it arrived we dissolved it in water at 1mg/mL so we could volumetrically measure 2mg doses accurately. Our first test doses were 500ug. It took us so long to get though the jar that some mold started to grow on the solution, even though we kept it in the fridge! Not wanting to throw hundreds of doses down the drain we scooped off the mold, added Everclear (ethanol), redid our concentration math, and moved the jar to the freezer. Wild, innocent times. Sadly, one of my friends in on the desoxypipradrol jar died from fentanyl contaminated dark web drugs a couple years ago. [1] https://en.wikipedia.org/wiki/Desoxypipradrol https://en.wikipedia.org/wiki/Desoxypipradrol
    - henryaj 2y ago
      That stuff looks fucking terrifying. Incredibly potent and super lipophilic so long-acting...

pprotas 2y ago

Be careful with 3-MMC. It’s rampant in The Netherlands, everyone and their mom is using it as a party drug. 16 year old kids are getting addicted and I have multiple friends that went to rehab for it. Pretty sure I damaged my kidney with it as well.

jamil7 2y ago

3-MMC is huge in Europe at the moment, never tried it but would be a little wary of it as I haven’t found a lot of reliable information on it.

nirse 2y ago
This should be a reliable source on 3mmc, but it is in Dutch: https://www.trimbos.nl/aanbod/webwinkel/af1916-factsheet-3mmc/ https://www.trimbos.nl/aanbod/webwinkel/af1916-factsheet-3mm...
- jamil7 2y ago
  Thanks
stampedbox 2y ago
https://www.erowid.org/experiences/subs/exp_3Methylmethcathinone.shtml https://www.erowid.org/experiences/subs/exp_3Methylmethcathi... and it's related chemical https://www.erowid.org/chemicals/4_methylmethcathinone/4_methylmethcathinone.shtml https://www.erowid.org/chemicals/4_methylmethcathinone/4_met...

otherme123 2y ago

Careful! Analogs can be very different in toxicity and other properties: some people drink ethanol on a daily basis, and damage is relatively low. Methanol is similar, but is very toxic and can damage and kill you easily. R-Thalidomide is used as anti-inflamatory and sedative, L-Thalidomide is teratogenic; and what is worse, one form can switch into the other form. The difference between Morphine and Codeine is minimal: a H is changed to a CH3. But one is 10x stronger than the other. In fact, morphine is more similar to codeine than to heroin. There is another opioid called Oripavine, similar to morphine (and can be transformed easily into), that is known to also have analgesic effects, but can't be used because it's highly toxic. It can itself be derived to M320, which is around 10000x more potent than morphine. In the opioid large family we could do this all day, with analogs and very similar molecules having a wild range of potency and toxicity. Don't use similarity between derivatives as a guide or a scale of their potential toxicity. I agree that the easiest and safest way to deal with this is to just legalize all drugs. IMO that will have at least two desirable effects: you will know exactly what you are consuming instead of betting on a derivative, and the race after analogs will stop: people will just consume what is known to be safe and effective, as it happens with alcohol.

dusted 2y ago
Funny thing with codine is that it's metabolized into morphine, and this happens at vastly different rates, from "not effective as a treatment" to "somewhat high risk of abuse due to euphoria"
LoganDark 2y ago
> I agree that the easiest and safest way to deal with this is to just legalize all drugs. IMO that will have at least two desirable effects: you will know exactly what you are consuming instead of betting on a derivative, and the race after analogs will stop: people will just consume what is known to be safe and effective, as it happens with alcohol. Amen. I'll be happy once I can pick up, say, LSD, from a pharmacy, and know that it's dosed accurately and unadulterated. Right now one would kinda have to buy it from either some guy or some darknet vendor and the only way to know it's safe is to test it with reagents. Those who don't test it run the risk of dying or suffering permanent damage from overdosing on some adulterant or substitute. It would probably also help with the current opioid crisis where people are dying because their doses are adulterated with fentanyl. Just offer doses that don't have fentanyl in it! Let people buy it from a safe regulated source.

pantalaimon 2y ago

Unfortunately a lot of 3-MMC sold these days is actually 3-CMC which is thought to be a lot more neurotoxic.

walthamstow 2y ago

4-MMC for £10 a gram in 2010, bought and sold legally, those were the days. God, it really stunk though.

stampedbox 2y ago

[dead]

jzemeocala 2y ago

I don't know if 3-mmc ever got a street name but it's got a sister compound 4-mmc that's commonly called mephedrone

deleted 2y ago

[deleted]