3 ms·

What’s the consensus on Ozempic/Wegovy/Semaglutide in the long term? Is this something you have to take forever otherwise risk rebound due to non-suppression o

by xyst 2y ago

What’s the consensus on Ozempic/Wegovy/Semaglutide in the long term? Is this something you have to take forever otherwise risk rebound due to non-suppression of desire for “sweet, savory, and salty” foods?

nyokodo 2y ago
> What’s the consensus on Ozempic/Wegovy/Semaglutide in the long term? Is this something you have to take forever otherwise risk rebound Yes, although it’s not exactly a consensus it was indicated in the original studies. This is a class of medication for treating chronic illness it is not intended as a short term intervention.
sodality2 2y ago
The consensus from what I have heard is that it helps you while you're taking it. Most people simply regain the weight if they stop taking, albeit at a lower rate. However, there is something to be said for the fortitude required to stay at a healthy weight, versus to reach a healthy weight, especially when your habits have been put on pause for a while. It's likely easier to break it long-term if you take the drug for a period of time first.
39896880 2y ago
Yes. You have to take it for the rest of your life, pretty common with drugs to treat chronic illnesses.
- okdood64 2y ago
  > chronic illnesses Is the chronic illness here a very high appetite and being hungry all the time? What exactly accounts for some people overeating and others not? (Genuine question, I'm trying to learn more about this area.)
  - orwin 2y ago
    Yes to both. Also, this might vary, but hunger used to hurt a lot to me. The thing that helped was going on a 5 day fast (prepared, with a doctor approbation) and especially going through the pain on the 2nd day, which hurt more than when I broke my ankle, probably the worst pain I remember. Nowadays, being hungry doesn't hurt as much, so I can easily let myself go hungry,and I'm at a healthy BMI.
  - 39896880 2y ago
    The chronic illness is obesity. GLP-1 drugs are being used to treat obesity.

by xyst 2y ago

nyokodo 2y ago

> What’s the consensus on Ozempic/Wegovy/Semaglutide in the long term? Is this something you have to take forever otherwise risk rebound Yes, although it’s not exactly a consensus it was indicated in the original studies. This is a class of medication for treating chronic illness it is not intended as a short term intervention.

sodality2 2y ago

The consensus from what I have heard is that it helps you while you're taking it. Most people simply regain the weight if they stop taking, albeit at a lower rate. However, there is something to be said for the fortitude required to stay at a healthy weight, versus to reach a healthy weight, especially when your habits have been put on pause for a while. It's likely easier to break it long-term if you take the drug for a period of time first.

39896880 2y ago

Yes. You have to take it for the rest of your life, pretty common with drugs to treat chronic illnesses.

okdood64 2y ago
> chronic illnesses Is the chronic illness here a very high appetite and being hungry all the time? What exactly accounts for some people overeating and others not? (Genuine question, I'm trying to learn more about this area.)
- orwin 2y ago
  Yes to both. Also, this might vary, but hunger used to hurt a lot to me. The thing that helped was going on a 5 day fast (prepared, with a doctor approbation) and especially going through the pain on the 2nd day, which hurt more than when I broke my ankle, probably the worst pain I remember. Nowadays, being hungry doesn't hurt as much, so I can easily let myself go hungry,and I'm at a healthy BMI.
- 39896880 2y ago
  The chronic illness is obesity. GLP-1 drugs are being used to treat obesity.