> Is it? It's part of the standard HIV therapy, which means it's being given to literally millions of people on a regular basis. A generic version is approved

> Is it? It's part of the standard HIV therapy, which means it's being given to literally millions of people on a regular basis. A generic version is approved in the US, and probably elsewhere, which means that more than one company is making it. It's a WHO-listed essential medicine. Short of ibuprofen or something, that's about as "at scale" as it gets for drugs. > The crux of the issue seems to be that this can't be reliably crystalized under gravity and the issue of "disappearing polymorphs" can be avoided. Apparently it can be crystallized reliably enough to support heavy use. There was a bad problem in 1998 where a more stable, but less potent, form was showing up. Apparently if there's even a tiny bit of that in a batch, it propagates and ruins the whole batch, so forward microcontamination was ruining all the batches. I think that was the first time anybody knew that that form even existed. My guess is that that is happening in approximately zero batches right now. But even if it's ruining half the batches, throwing them away is still cheaper than trying to do it in space.