2 ms·
the "article" you linked is a bulleted list of timestamps into a podcast from December 4, 2023. Near minute 57, they're talking about tissue samples from eutha
by schaefer 3y ago
the "article" you linked is a bulleted list of timestamps into a podcast from December 4, 2023. Near minute 57, they're talking about tissue samples from euthanized mice... And mention "(58:15) no one at this point knows what tissue to look at" If you want to get more specific than that with timestamps, it might aid in further discussion.
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But, clearly these podcast participants (from 2023) hadn't read this study from Feb 20th 2024. And the study seems quite clear what biomarkers they're measuring:
"Biological age estimates have been developed to approximate the level of aging and subsequent morbidity and mortality risk for an individual. Estimates based on clinical chemistry typically combine multi-system biomarkers (here: albumin, alkaline phosphatase, serum creatinine, C-reactive protein, Hba1c, systolic blood pressure, and total cholesterol) into a single variable meant to capture the level and rate of organismal aging44,45,46,47,48 (Table S2)."
- nradov 3y agoYou're really missing the point. None of that constitutes evidence that those biomarkers are reliable indicators of whether a particular intervention has actually changed a human subject's expected lifespan.