Oh, cool- they turned a not-truly-a-knot (open ends) protein into a truly knotted one (connected ends) and then unfolded it using urea and it stayed knotted. T

Oh, cool- they turned a not-truly-a-knot (open ends) protein into a truly knotted one (connected ends) and then unfolded it using urea and it stayed knotted. That's what you'd expect but it's also pretty cool.