5 ms·

Can't believe people still drink soda, or let their kids drink that shit.

by demondemidi 3y ago

throwaway743950 3y ago
[flagged]
- beretguy 3y ago
  Which drinks have dhmo?
  - throwaway743950 3y ago
    The majority. See https://en.wikipedia.org/wiki/Dihydrogen_monoxide_parody https://en.wikipedia.org/wiki/Dihydrogen_monoxide_parody Jokes aside, soda is typically loaded with sugar, but diet sodas don't seem as bad.
    - swader999 3y ago
      Aspartame though.
      - PeterHolzwarth 3y ago
        Aspartame is profoundly safe and there is no mechanism through which it could be unsafe in the human body.
        RadixDLT 3y ago
        stevia is the safest
        PeterHolzwarth 3y ago
        Where has that been demonstrated? Aspartame is one of the most ridiculously well-studied food additives known to humankind.
        trehalose 3y ago
        Well, there's phenylketonuria. (That's not relevant to the vast majority of people, but it's an extremely important exception.)
        PeterHolzwarth 3y ago
        Phenylketonuria is an inherited genetic disorder. Aspartame doesn't make a food unsafe to those who do not suffer from this genetic disorder any more than peanuts do for people who do not have nut allergies.
        deleted 3y ago
        [deleted]
        TheCleric 3y ago
        I think there’s more and more research coming out disproving this. Aspartame’s flavor can cause insulin release from the pancreas which lowers your body’s insulin sensitivity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/
tgsovlerkhgsel 3y ago
Can't believe people do anything enjoyable, or let their kids do anything enjoyable. https://www.youtube.com/watch?v=WPz9Fcvb1II https://www.youtube.com/watch?v=WPz9Fcvb1II
- ClumsyPilot 3y ago
  The ratio of Harm to Enjoyment varies, some activities seem not worth it. Like taking cocaime or drinking soda have surprisingly similar ratio - soda has so little fun but considerable harm, so the ratio is very poor
  - jurynulifcation 3y ago
    Cocaine taken as a tea from coca leaf is actually pretty great. It's like coffee tier 2. Harm to Enjoyment ratio might even dip below unity since, based on some research papers I've read, I think cocaine might not be as bad as caffeine (in sane quantities). Snorting coke is pretty worthless, but so is snorting caffeine.
    - galangalalgol 3y ago
      Snorting caffeine in similar quantities to cocaine would be lethal wouldn't it?
      - jurynulifcation 3y ago
        I haven't been able to confirm nor refute this. However, being sloppy, it looks like pure cocaine has an LD50 of about 95 mg/kg [1] while caffeine appears to have an LD50 of about 367mg/kg [2]. These are numbers from rat and mouse studies, with different routes of administration. The cocaine LD50, for instance, was obtained by IP (intraperitoneal) injection, while the caffeine administration was oral. I have not been able to find any studies that give an LD50 for both substances in a single animal model with the same route of administration. Let's play with these numbers as they are. The IC50 (inhibitory constant, a measure of sufficiency of plasma concentration to inhibit 50% of affected biological processes [how I'll estimate potency]) of caffeine in the human model is estimated at a concentration of about 67microMolar. Cocaine's IC50 appears to be about 4.4mM.[4] The major difference in routes of administration will be how much of the substance ends up in plasma vs metabolites. Making the genuinely wild assumption that they have similar plasma effects from the same RoA, it would appear the IC50 of cocaine is about an order magnitude lower than that of caffeine (meaning you need less), while its LD50 is about a third that of caffeine (meaning less will kill you [but also keeping in mind that the LD50 was found via injections]) but still within the same order of magnitude approximation. This to me indicates that cocaine is the preferable compound, even though I still think neither of them is great intransally. I will say, however, I absolutely prefer my cocaine as a drink and caffeine as a snifter. I have an intranasal cocktail of oxytocin, kanna, and caffeine that I'll bump once or twice a week. I quite like it, but people who rail lines of caffeine simply befuddle me. [1] https://pubmed.ncbi.nlm.nih.gov/7178201/ https://pubmed.ncbi.nlm.nih.gov/7178201/ [2] https://pubmed.ncbi.nlm.nih.gov/27461039/ https://pubmed.ncbi.nlm.nih.gov/27461039/ [3] https://jnm.snmjournals.org/content/jnumed/early/2012/09/07/jnumed.112.105114.full.pdf https://jnm.snmjournals.org/content/jnumed/early/2012/09/07/... [4] https://pubmed.ncbi.nlm.nih.gov/11561083/ https://pubmed.ncbi.nlm.nih.gov/11561083/
Dalewyn 3y ago
I drink some Coke every once in a while when I'm partway through a long day and need something to give me a kick. Between the burst of sugar and caffeine, that's one mighty kick.
basisword 3y ago
I avoided soft drinks for a long time but slipped into it during the pandemic. 2-3 cans of Coke Zero per day. 1. I had perfect dental health all my life and needed multiple fillings after 18 months of soda. 2. That shit is addictive! I swear quitting cigarettes was waaay easier than quitting soda.
- canjobear 3y ago
  Counter-anecdote: I have drunk 1-2 Coke Zeros every day for years, enjoy it a lot, and have had excellent dental health.
  - willywanker 3y ago
    Do you also frequently rinse your mouth? Oral hygiene will also determine dental health, not just soda consumed.
- bscphil 3y ago
  > I had perfect dental health all my life and needed multiple fillings after 18 months of soda. Not an expert, but I'm not sure if that makes sense? As I understand it, soda causes dental problems because bacteria in your mouth eat sugar, creating an acidic environment that erodes the enamel on your teeth, making it possible for cavities to form. Since Coke Zero doesn't contain sugar, I don't see why it would be a problem. I wonder if you normally had regular 6 month or 12 month dental checkups, where they would clean built-up tartar off your teeth, and these were put on hold during the pandemic?
  - jonhohle 3y ago
    Is that true for HFCS as well? Whenever I’m overseas and get real sugar sodas my teeth always feel much “fuzzier” by the end of the day. I never get that feeling with US corn-sweetened sodas.
  - OldManAndTheCpp 3y ago
    Sodas also have acid in them directly, the first 3 ingredients in Coke Zero are: > CARBONATED WATER, CARAMEL COLOR, PHOSPHORIC ACID, … https://us.coca-cola.com/products/coca-cola-zero-sugar/coca-cola-zero-sugar https://us.coca-cola.com/products/coca-cola-zero-sugar/coca-...

Can't believe people still drink soda, or let their kids drink that shit.

throwaway743950 3y ago

[flagged]

beretguy 3y ago
Which drinks have dhmo?
- throwaway743950 3y ago
  The majority. See https://en.wikipedia.org/wiki/Dihydrogen_monoxide_parody https://en.wikipedia.org/wiki/Dihydrogen_monoxide_parody Jokes aside, soda is typically loaded with sugar, but diet sodas don't seem as bad.
  - swader999 3y ago
    Aspartame though.
    - PeterHolzwarth 3y ago
      Aspartame is profoundly safe and there is no mechanism through which it could be unsafe in the human body.
      - RadixDLT 3y ago
        stevia is the safest
        PeterHolzwarth 3y ago
        Where has that been demonstrated? Aspartame is one of the most ridiculously well-studied food additives known to humankind.
      - trehalose 3y ago
        Well, there's phenylketonuria. (That's not relevant to the vast majority of people, but it's an extremely important exception.)
        PeterHolzwarth 3y ago
        Phenylketonuria is an inherited genetic disorder. Aspartame doesn't make a food unsafe to those who do not suffer from this genetic disorder any more than peanuts do for people who do not have nut allergies.
      - deleted 3y ago
        [deleted]
      - TheCleric 3y ago
        I think there’s more and more research coming out disproving this. Aspartame’s flavor can cause insulin release from the pancreas which lowers your body’s insulin sensitivity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/

tgsovlerkhgsel 3y ago

Can't believe people do anything enjoyable, or let their kids do anything enjoyable. https://www.youtube.com/watch?v=WPz9Fcvb1II https://www.youtube.com/watch?v=WPz9Fcvb1II

ClumsyPilot 3y ago
The ratio of Harm to Enjoyment varies, some activities seem not worth it. Like taking cocaime or drinking soda have surprisingly similar ratio - soda has so little fun but considerable harm, so the ratio is very poor
- jurynulifcation 3y ago
  Cocaine taken as a tea from coca leaf is actually pretty great. It's like coffee tier 2. Harm to Enjoyment ratio might even dip below unity since, based on some research papers I've read, I think cocaine might not be as bad as caffeine (in sane quantities). Snorting coke is pretty worthless, but so is snorting caffeine.
  - galangalalgol 3y ago
    Snorting caffeine in similar quantities to cocaine would be lethal wouldn't it?
    - jurynulifcation 3y ago
      I haven't been able to confirm nor refute this. However, being sloppy, it looks like pure cocaine has an LD50 of about 95 mg/kg [1] while caffeine appears to have an LD50 of about 367mg/kg [2]. These are numbers from rat and mouse studies, with different routes of administration. The cocaine LD50, for instance, was obtained by IP (intraperitoneal) injection, while the caffeine administration was oral. I have not been able to find any studies that give an LD50 for both substances in a single animal model with the same route of administration. Let's play with these numbers as they are. The IC50 (inhibitory constant, a measure of sufficiency of plasma concentration to inhibit 50% of affected biological processes [how I'll estimate potency]) of caffeine in the human model is estimated at a concentration of about 67microMolar. Cocaine's IC50 appears to be about 4.4mM.[4] The major difference in routes of administration will be how much of the substance ends up in plasma vs metabolites. Making the genuinely wild assumption that they have similar plasma effects from the same RoA, it would appear the IC50 of cocaine is about an order magnitude lower than that of caffeine (meaning you need less), while its LD50 is about a third that of caffeine (meaning less will kill you [but also keeping in mind that the LD50 was found via injections]) but still within the same order of magnitude approximation. This to me indicates that cocaine is the preferable compound, even though I still think neither of them is great intransally. I will say, however, I absolutely prefer my cocaine as a drink and caffeine as a snifter. I have an intranasal cocktail of oxytocin, kanna, and caffeine that I'll bump once or twice a week. I quite like it, but people who rail lines of caffeine simply befuddle me. [1] https://pubmed.ncbi.nlm.nih.gov/7178201/ https://pubmed.ncbi.nlm.nih.gov/7178201/ [2] https://pubmed.ncbi.nlm.nih.gov/27461039/ https://pubmed.ncbi.nlm.nih.gov/27461039/ [3] https://jnm.snmjournals.org/content/jnumed/early/2012/09/07/jnumed.112.105114.full.pdf https://jnm.snmjournals.org/content/jnumed/early/2012/09/07/... [4] https://pubmed.ncbi.nlm.nih.gov/11561083/ https://pubmed.ncbi.nlm.nih.gov/11561083/

Dalewyn 3y ago

I drink some Coke every once in a while when I'm partway through a long day and need something to give me a kick. Between the burst of sugar and caffeine, that's one mighty kick.

basisword 3y ago

I avoided soft drinks for a long time but slipped into it during the pandemic. 2-3 cans of Coke Zero per day. 1. I had perfect dental health all my life and needed multiple fillings after 18 months of soda. 2. That shit is addictive! I swear quitting cigarettes was waaay easier than quitting soda.

canjobear 3y ago
Counter-anecdote: I have drunk 1-2 Coke Zeros every day for years, enjoy it a lot, and have had excellent dental health.
- willywanker 3y ago
  Do you also frequently rinse your mouth? Oral hygiene will also determine dental health, not just soda consumed.
bscphil 3y ago
> I had perfect dental health all my life and needed multiple fillings after 18 months of soda. Not an expert, but I'm not sure if that makes sense? As I understand it, soda causes dental problems because bacteria in your mouth eat sugar, creating an acidic environment that erodes the enamel on your teeth, making it possible for cavities to form. Since Coke Zero doesn't contain sugar, I don't see why it would be a problem. I wonder if you normally had regular 6 month or 12 month dental checkups, where they would clean built-up tartar off your teeth, and these were put on hold during the pandemic?
- jonhohle 3y ago
  Is that true for HFCS as well? Whenever I’m overseas and get real sugar sodas my teeth always feel much “fuzzier” by the end of the day. I never get that feeling with US corn-sweetened sodas.
- OldManAndTheCpp 3y ago
  Sodas also have acid in them directly, the first 3 ingredients in Coke Zero are: > CARBONATED WATER, CARAMEL COLOR, PHOSPHORIC ACID, … https://us.coca-cola.com/products/coca-cola-zero-sugar/coca-cola-zero-sugar https://us.coca-cola.com/products/coca-cola-zero-sugar/coca-...