3 ms·
>Two of six mice exposed to 70% methane in air died in 18 min, whereas mice exposed to 70% nitrogen in air developed only ataxia. Animals exposed to 50-90% meth
by wil421 3y ago
>Two of six mice exposed to 70% methane in air died in 18 min, whereas mice exposed to 70% nitrogen in air developed only ataxia. Animals exposed to 50-90% methane in oxygen showed mild depression and a marked decrease in locomotion, but no ataxia. Thus, the toxic effect of methane is much greater than that of nitrogen when available oxygen is low, but methane has little effect when oxygen is readily available.
It seems that the toxicity of methane should be discussed not alone, but rather with respect to the partial pressure of oxygen in the atmosphere in question.
https://www.ncbi.nlm.nih.gov/books/NBK208285/#:~:text=Thus%2C%20the%20toxic%20effect%20of,when%20oxygen%20is%20readily%20available https://www.ncbi.nlm.nih.gov/books/NBK208285/#:~:text=Thus%2....
- MikusR 3y agohttps://twitter.com/justsaysinmice https://twitter.com/justsaysinmice
- Someone 3y agoWhat is “70% nitrogen in air”? https://en.wikipedia.org/wiki/Atmosphere_of_Earth https://en.wikipedia.org/wiki/Atmosphere_of_Earth: “As of 2023, by mole fraction (i.e., by number of molecules), dry air contains 78.08% nitrogen, 20.95% oxygen, 0.93% argon, 0.04% carbon dioxide, and small amounts of other gases.” Did they take out nitrogen, added 7 parts nitrogen to 10 parts of air, use something else than mole fraction, …?
- Dylan16807 3y agoI guess by that measure sandwiches are toxic because if you replace someone's water intake with sandwiches they'll die.