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Doesn't look very impressive. Lots of overlap in the scatter graphs, and no mention of whether they corrected for multiple comparisons. Overall it looks like th
by cpncrunch 3y ago
Doesn't look very impressive. Lots of overlap in the scatter graphs, and no mention of whether they corrected for multiple comparisons. Overall it looks like the typical breathless press release clickbait that HN users seem to constantly post here.
- azan_ 3y agoThey did correct for multiple testing - "P-values were multiple-test corrected using the Benjamini-Hochberg False Discovery Rate (FDR) procedure and a cutoff of 0.1 was applied to select the differentially abundant genera". However, they used Wilcoxon test which has unacceptably high FDR [1]. [1] https://www.nature.com/articles/s41467-022-28034-z https://www.nature.com/articles/s41467-022-28034-z