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> Promising results from an initial clinical trial at the Austin Hospital in Melbourne, published today in Critical Care, show that sodium ascorbate – a pH-bala
by thenerdhead 3y ago
> Promising results from an initial clinical trial at the Austin Hospital in Melbourne, published today in Critical Care, show that sodium ascorbate – a pH-balanced formulation of vitamin C – is effective in treating sepsis
> “In our trial at Austin Hospital, patients were given sodium ascorbate into their bloodstream, resulting in promising improvements to multiple organs.”
Oh boy, vitamin C is having a very strange year. First cancer, now sepsis.
- irrational 3y agoWhat is the vitamin C and cancer thing? Vitamin C causes cancer?
- thenerdhead 3y agoTaking C and E makes some cancers grow faster. But also mega dosing C can help improve some cancers. Lots of back and forth.
- WithinReason 3y agoWhat do you mean by "improving" cancer?
- pazimzadeh 3y agoIt's the delivery method that is the difference, not just the dose. Vitamin C IV is pro-oxidant (promotes damage to mitochondria (cancers have famously messed up mitochondria already), etc) whereas Vitamin C that passes through the gut is anti-oxidant. https://www.cancer.gov/research/key-initiatives/ras/ras-central/blog/2020/yun-cantley-vitamin-c https://www.cancer.gov/research/key-initiatives/ras/ras-cent...
- thenerdhead 3y agoAh yes! That's one I was looking to link. Specifically Mark Levine's work. i.e. https://pubmed.ncbi.nlm.nih.gov/15068981/ https://pubmed.ncbi.nlm.nih.gov/15068981/
- nikolay 3y agoI've read that vitamin C over 500mg even oral causes mitochondrial damage.
- cyberax 3y agoThis kinda makes sense. Cancer cells are under severe oxidative pressure, and vitamin C in reasonable doses is an anti-oxidant. But in _very_ high doses another mechanism kicks in, and the vitamin C causes generation of reactive oxygen species: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285147/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285147/
- deleted 3y ago[deleted]