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You should edit your comment to specify that you are referring to Type 2 diabetes. As stated in the article, infection by coronavirus and many other viruses can

You should edit your comment to specify that you are referring to Type 2 diabetes. As stated in the article, infection by coronavirus and many other viruses can trigger Type 1 diabetes through autoimmune reactions. (Which I think most people would interpret as "directly causes" for all practical purposes.)

defrost 3y ago
Thank you for your opinion. As stated in the article: ... and may lead to diabetes. 'May' is a qualifying word and that sentence is immediately followed by: Additionally, diabetes risk factors may have been exacerbated during the COVID-19 pandemic including ... (Which I think most people would interpret as "nothing is entirely certain thus far, it appears to be a complex multifactor kind of thing".) FWiW I addressed the title and the article's primary focus, Type-2 diabetes, and linked to detailed comparative factor breakdowns for Type-2 diabetes.
haldujai 3y ago
Nothing in this paper is anywhere close to establishing causality, it's an interesting observation that merits further study. We should also note that the authors offer alternative possibilities in the discussion such as increased/early diagnosis. Interestingly, the 10-19 T1D IRR declines below prepandemic levels in Q4 2021 which would be supportive of this hypothesis for this age group however more follow-up is needed to see how the trend evolves.
- anon84873628 3y ago
  My point is that we do know viruses "directly cause" Type 1 diabetes -- which still has lots of interesting research questions -- but they are quite different from questions about the effect of lockdowns on Type 2 diabetes. Lockdowns being the obvious middle step we are all wondering about that connects the virus to the disease "indirectly".
  - haldujai 3y ago
    > My point is that we do know viruses "directly cause" Type 1 diabetes If you mean virus are capable of directly causing T1D in theory and animal models, sure. As to whether this actually happens to humans in real life is as clear as mud. There is also similarly weak evidence that says viruses have either no or a protective role in the pathogenesis of T1D.
pfannkuchen 3y ago
> coronavirus and many other viruses can trigger Does COVID trigger this at a higher rate than other viruses? Or did the overall rate of viral infection increase due to covid? I suspect the answers are “we don’t know” and “not substantially”.
- anon84873628 3y ago
  Sure. But the point is that as far as casual factors go, the research questions for T1 vs T2 diabetes are going to be fairly different. I personally think it is important to be clear what we are talking about, and that the article itself is written poorly in this regard.

defrost 3y ago

Thank you for your opinion. As stated in the article: ... and may lead to diabetes. 'May' is a qualifying word and that sentence is immediately followed by: Additionally, diabetes risk factors may have been exacerbated during the COVID-19 pandemic including ... (Which I think most people would interpret as "nothing is entirely certain thus far, it appears to be a complex multifactor kind of thing".) FWiW I addressed the title and the article's primary focus, Type-2 diabetes, and linked to detailed comparative factor breakdowns for Type-2 diabetes.

haldujai 3y ago

Nothing in this paper is anywhere close to establishing causality, it's an interesting observation that merits further study. We should also note that the authors offer alternative possibilities in the discussion such as increased/early diagnosis. Interestingly, the 10-19 T1D IRR declines below prepandemic levels in Q4 2021 which would be supportive of this hypothesis for this age group however more follow-up is needed to see how the trend evolves.

anon84873628 3y ago
My point is that we do know viruses "directly cause" Type 1 diabetes -- which still has lots of interesting research questions -- but they are quite different from questions about the effect of lockdowns on Type 2 diabetes. Lockdowns being the obvious middle step we are all wondering about that connects the virus to the disease "indirectly".
- haldujai 3y ago
  > My point is that we do know viruses "directly cause" Type 1 diabetes If you mean virus are capable of directly causing T1D in theory and animal models, sure. As to whether this actually happens to humans in real life is as clear as mud. There is also similarly weak evidence that says viruses have either no or a protective role in the pathogenesis of T1D.

pfannkuchen 3y ago

> coronavirus and many other viruses can trigger Does COVID trigger this at a higher rate than other viruses? Or did the overall rate of viral infection increase due to covid? I suspect the answers are “we don’t know” and “not substantially”.

anon84873628 3y ago
Sure. But the point is that as far as casual factors go, the research questions for T1 vs T2 diabetes are going to be fairly different. I personally think it is important to be clear what we are talking about, and that the article itself is written poorly in this regard.