> In the mediation effect analyses, BMI, CRP, and TyG (fasting triglyceride-glucose) index did not mediate the association between breakfast frequency and the r

> In the mediation effect analyses, BMI, CRP, and TyG (fasting triglyceride-glucose) index did not mediate the association between breakfast frequency and the risk of GI cancer incidence (all P for mediation effect > 0.05). Meshes with all of the other studies that show no benefit to TRF or IF unrelated to weight-loss (which can be achieved without TRF/IF), and the studies showing harm, like this one: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182756/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182756/ and this one: https://www.researchgate.net/publication/368542960_Insulin_resistance_after_a_3-day_fast_is_associated_with_an_increased_capacity_of_skeletal_muscle_to_oxidize_lipids https://www.researchgate.net/publication/368542960_Insulin_r...