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Not sure what the relevance of cardiac cirrhosis is to this discussion? You’re talking about an uncommon end stage complication of chronic severe right heart f

Not sure what the relevance of cardiac cirrhosis is to this discussion? You’re talking about an uncommon end stage complication of chronic severe right heart failure. To the parent comment’s question: yes, prevention is better. If you prevent right heart failure you will not get cardiac cirrhosis. The old adage of “an ounce of prevention is better than a pound of cure” is still true.

rolph 3y ago
>>Perhaps this is a naive question, but wouldn’t a preventative measure for heart disease<< preventive and corrective measures, in response to health issues should be instituted in the context of the whole organism[patient] cardiac cirrhosis, is an example of secondary pathology related to a common set of disease conditions [heart disease]. correction of pathologic state of one organ via stem cell therapy, is a start but is not complete, heart disease is not always preventable by way of lifestyle choices, as genetic, and traumatic causes will effect occurence. protracted illness often leads to secondary, or even, systemic issues concurrently presenting, at time of first examination. any therapy must take this context into account. The old adage of “an ounce of prevention is better than a pound of cure” is only true, when prevention is possible.
- haldujai 3y ago
  Cardiac cirrhosis is just a bad example, it’s difficult to estimate prevalence but it’s very rare and even then most cases don’t matter as it reflects a state of severe systemic dysfunction (i.e. patient is on deaths door for several other reasons). Fixing the heart at that point won’t accomplish anything with respects to cirrhosis. Right sided heart failure is also rare outside of advanced LHF or preventable causes of pHTN. Congestive heart failure as a whole was attributable to preventable causes in something like 95% of cases in the NHANES cohort. The 5% of other cases is variable but sure, some are not preventable. Point being that prevention is possible and remains the preferred approach for the overwhelming majority of people, as the parent comment was inquiring about: > Perhaps this is a naive question, but wouldn’t a preventative measure for heart disease (stopping obesity via, say, ozempic) do more for longevity than repairing the heart after dysfunction has taken root?

rolph 3y ago

>>Perhaps this is a naive question, but wouldn’t a preventative measure for heart disease<< preventive and corrective measures, in response to health issues should be instituted in the context of the whole organism[patient] cardiac cirrhosis, is an example of secondary pathology related to a common set of disease conditions [heart disease]. correction of pathologic state of one organ via stem cell therapy, is a start but is not complete, heart disease is not always preventable by way of lifestyle choices, as genetic, and traumatic causes will effect occurence. protracted illness often leads to secondary, or even, systemic issues concurrently presenting, at time of first examination. any therapy must take this context into account. The old adage of “an ounce of prevention is better than a pound of cure” is only true, when prevention is possible.

haldujai 3y ago
Cardiac cirrhosis is just a bad example, it’s difficult to estimate prevalence but it’s very rare and even then most cases don’t matter as it reflects a state of severe systemic dysfunction (i.e. patient is on deaths door for several other reasons). Fixing the heart at that point won’t accomplish anything with respects to cirrhosis. Right sided heart failure is also rare outside of advanced LHF or preventable causes of pHTN. Congestive heart failure as a whole was attributable to preventable causes in something like 95% of cases in the NHANES cohort. The 5% of other cases is variable but sure, some are not preventable. Point being that prevention is possible and remains the preferred approach for the overwhelming majority of people, as the parent comment was inquiring about: > Perhaps this is a naive question, but wouldn’t a preventative measure for heart disease (stopping obesity via, say, ozempic) do more for longevity than repairing the heart after dysfunction has taken root?