4 ms·

All of your sources are about acute or active covid infection. As a physician who worked in an ECMO center during the pandemic I am well aware of severe Covid-1

All of your sources are about acute or active covid infection. As a physician who worked in an ECMO center during the pandemic I am well aware of severe Covid-19 infections and as I stated in my post I tried searching, specifically looking on: UpToDate, Medscape and Google Scholar. I am asking about "long-covid", also called "post covid condition". From Brandon's own description he had what would be classified as "mild COVID-19 illness" and was never hospitalized. He had some persistent symptoms that may be attributable to "long-covid", this is very different from your sources. I have never heard of a death from long-term sequelae in someone who has never been hospitalized.

deleted 3y ago
[deleted]
latchkey 3y ago
The first link was about repeat infections. It seems possible that he could have had multiple infections and then that caused MoD? > As a physician Oh, you didn't mention that in the first post... I'm sure you know better than I.
- haldujai 3y ago
  > The first link was about repeat infections. It seems possible that he could have had multiple infections and then that caused MoD? His timeline on the Google document ends in April 2023 when he reported he was slowly improving. It's certainly possible another infection resulted in multi-organ failure and unfortunately his death but that would be "acute covid" and not "long-covid". > Oh, you didn't mention that in the first post... I'm sure you know better than I. I don't see long-covid in my practice and hence why I'm asking. I know some of the literature around it and tried searching without success, I'm wondering if someone who knows more can fill in some of the blanks here.
ck2 3y ago
As someome going through something similar to Brandon but a bit less severe let me plant this thought in your process: The initial covid infection can be a "death blow" for some people, especially if genetically at risk for long-covid (as proven in recent studies) Just like Brandon I had a near fatal covid infection in 2020, I was on 24/7 oxygen for two months and never fully recovered. I've stabilized but it is clear I am on a slow but steady decline over the past few years and if this slope continues, I could end up like Brandon. So if I die in a couple years from Long-Covid, are you going to argue it's not long-covid that killed me or the original covid infection? Because the damage persists and is getting worse even without active infection. There are several papers on premature aging (aka radical aging) from covid->long-covid, the ultimate final outcome of that is organ failure and death many years, decades, before one's time. Look at his twitter and you'll see some of his photos, he was not well and that's three years later after infection. https://twitter.com/BrandonGilles/with_replies https://twitter.com/BrandonGilles/with_replies Covid basically finds every genetic and environmental triggered weakness in the body and doesn't relent in some people. That's long-covid, at least one kind.
- haldujai 3y ago
  > Just like Brandon I had a near fatal covid infection in 2020, I was on 24/7 oxygen for two months and never fully recovered. He describes that he had mild infection both times and was not hospitalized. > So if I die in a couple years from Long-Covid, are you going to argue it's not long-covid that killed me or the original covid infection? I’m not “arguing” anything as this would suggest I have a viewpoint. I’m asking from a medical perspective if anyone knows of a reported case that investigated or described cause of death. Multi organ failure typically occurs in the ICU in extremely sick people, with an inciting event. I’m not following how ME/CFS leads to that. It could be that I’m uneducated on this, hence the question. You could swap “COVID” with many other diseases or pathogens and I would be similarly curious. It’s just an unusual progression in a < 40 year old. > https://twitter.com/BrandonGilles/with_replies https://twitter.com/BrandonGilles/with_replies Thanks for providing this, I read back until early June or so. It looks like he was taking Difficid, presumably for CDAD. Severe C diff can certainly result in multi organ failure and death. Unusual in an antibiotic naive patient and I’ve not heard of a link with COVID. He also in another tweet states he has hepatic encephalopathy. Is a sign of liver/end organ dysfunction. HE wasn’t on the linked timeline and is very rare in non-cirrhotics but has happened. This would typically be worked up looking for the cause. It would be medically interesting to see a liver biopsy results. Severe liver dysfunction could also explain multi organ failure and death. Brandon clearly put in a lot of effort when he was alive to publicly document and detail his journey which has been informative for me. My understanding is that he was hoping to increase awareness and provide resources for others. I’m looking for a report to fill in the gaps between what he has shared and his unfortunate death which is medically very interesting. This is not, and should not, be a debate about the validity of serious COVID illness or CE/MFS which has been established at this point.

deleted 3y ago

[deleted]

latchkey 3y ago

The first link was about repeat infections. It seems possible that he could have had multiple infections and then that caused MoD? > As a physician Oh, you didn't mention that in the first post... I'm sure you know better than I.

haldujai 3y ago
> The first link was about repeat infections. It seems possible that he could have had multiple infections and then that caused MoD? His timeline on the Google document ends in April 2023 when he reported he was slowly improving. It's certainly possible another infection resulted in multi-organ failure and unfortunately his death but that would be "acute covid" and not "long-covid". > Oh, you didn't mention that in the first post... I'm sure you know better than I. I don't see long-covid in my practice and hence why I'm asking. I know some of the literature around it and tried searching without success, I'm wondering if someone who knows more can fill in some of the blanks here.

ck2 3y ago

As someome going through something similar to Brandon but a bit less severe let me plant this thought in your process: The initial covid infection can be a "death blow" for some people, especially if genetically at risk for long-covid (as proven in recent studies) Just like Brandon I had a near fatal covid infection in 2020, I was on 24/7 oxygen for two months and never fully recovered. I've stabilized but it is clear I am on a slow but steady decline over the past few years and if this slope continues, I could end up like Brandon. So if I die in a couple years from Long-Covid, are you going to argue it's not long-covid that killed me or the original covid infection? Because the damage persists and is getting worse even without active infection. There are several papers on premature aging (aka radical aging) from covid->long-covid, the ultimate final outcome of that is organ failure and death many years, decades, before one's time. Look at his twitter and you'll see some of his photos, he was not well and that's three years later after infection. https://twitter.com/BrandonGilles/with_replies https://twitter.com/BrandonGilles/with_replies Covid basically finds every genetic and environmental triggered weakness in the body and doesn't relent in some people. That's long-covid, at least one kind.

haldujai 3y ago
> Just like Brandon I had a near fatal covid infection in 2020, I was on 24/7 oxygen for two months and never fully recovered. He describes that he had mild infection both times and was not hospitalized. > So if I die in a couple years from Long-Covid, are you going to argue it's not long-covid that killed me or the original covid infection? I’m not “arguing” anything as this would suggest I have a viewpoint. I’m asking from a medical perspective if anyone knows of a reported case that investigated or described cause of death. Multi organ failure typically occurs in the ICU in extremely sick people, with an inciting event. I’m not following how ME/CFS leads to that. It could be that I’m uneducated on this, hence the question. You could swap “COVID” with many other diseases or pathogens and I would be similarly curious. It’s just an unusual progression in a < 40 year old. > https://twitter.com/BrandonGilles/with_replies https://twitter.com/BrandonGilles/with_replies Thanks for providing this, I read back until early June or so. It looks like he was taking Difficid, presumably for CDAD. Severe C diff can certainly result in multi organ failure and death. Unusual in an antibiotic naive patient and I’ve not heard of a link with COVID. He also in another tweet states he has hepatic encephalopathy. Is a sign of liver/end organ dysfunction. HE wasn’t on the linked timeline and is very rare in non-cirrhotics but has happened. This would typically be worked up looking for the cause. It would be medically interesting to see a liver biopsy results. Severe liver dysfunction could also explain multi organ failure and death. Brandon clearly put in a lot of effort when he was alive to publicly document and detail his journey which has been informative for me. My understanding is that he was hoping to increase awareness and provide resources for others. I’m looking for a report to fill in the gaps between what he has shared and his unfortunate death which is medically very interesting. This is not, and should not, be a debate about the validity of serious COVID illness or CE/MFS which has been established at this point.