4 ms·

Except that whole chemical imbalance theory was thoroughly debunked earlier this year as not being the cause of depression, just a marketing gimmick used to sel

Except that whole chemical imbalance theory was thoroughly debunked earlier this year as not being the cause of depression, just a marketing gimmick used to sell more anti depressants by pharma companies... "The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression. Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants." https://www.ucl.ac.uk/news/2022/jul/analysis-depression-probably-not-caused-chemical-imbalance-brain-new-study https://www.ucl.ac.uk/news/2022/jul/analysis-depression-prob...

what-no-tests 3y ago
THIS needs to be spread around much more broadly. [UPDATE]: Looks like I'm getting downvoted by people who cling to their meds. Try physical activity and adjusting your self-talk. Try having goals and making steady progress toward them. What you need doesn't come from a pill, it comes from living life.
- mrguyorama 3y ago
  >What you need doesn't come from a pill, it comes from living life. Fuck off. Imagine telling someone with astigmatism that they don't need a physical modification and augmentation to their bodies, but rather "to live life", whatever that means. Meanwhile, after decades of swearing I didn't need a pill, I didn't want a pill to "change" me, etc, I got on pills, and my life actually works. I rode a rollercoaster for the first time in decades the other day, zero butterflies in my stomach, zero panic or anxiety, zero inappropriate fear. I'm likely only alive today BECAUSE of medication. The whole point behind how new medications are tested are that we often don't have a great understanding of HOW a medication works, but that doesn't matter, because it demonstrably works in some percentage of people, and for those that it doesn't work for, often another medication might. So, with zero respect because you are actively harming people, Fuck right off.
  - copperx 3y ago
    Thanks for saying that. Although I've resigned myself because I know that people will often not acknowledge and have empathy and understanding towards a condition if they haven't experienced it in their own skin. It's depressing, but it seems to be part of the human condition.
  - new6392689 3y ago
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- deleted 3y ago
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ethanbond 3y ago
1. A countervailing meta-analysis does not mean it's "debunked" 2. A theory being debunked does not mean it's "just a marketing gimmick" 3. The serotonin theory being debunked does not mean "chemical imbalance" is totally exonerated Great article though, thank you for sharing. Here's the paper itself for anyone interested (AFAICT it is oddly not linked in the UCL article?): https://pubmed.ncbi.nlm.nih.gov/35854107/ https://pubmed.ncbi.nlm.nih.gov/35854107/
- appleflaxen 3y ago
  Great points, but the word exonerated makes no sense in that context.
  - ethanbond 3y ago
    > to clear from accusation or blame Serotonin theory being debunked does not mean “chemical imbalance” is totally cleared from blame Seems clear enough to me, but noted for the future!

what-no-tests 3y ago

THIS needs to be spread around much more broadly. [UPDATE]: Looks like I'm getting downvoted by people who cling to their meds. Try physical activity and adjusting your self-talk. Try having goals and making steady progress toward them. What you need doesn't come from a pill, it comes from living life.

mrguyorama 3y ago
>What you need doesn't come from a pill, it comes from living life. Fuck off. Imagine telling someone with astigmatism that they don't need a physical modification and augmentation to their bodies, but rather "to live life", whatever that means. Meanwhile, after decades of swearing I didn't need a pill, I didn't want a pill to "change" me, etc, I got on pills, and my life actually works. I rode a rollercoaster for the first time in decades the other day, zero butterflies in my stomach, zero panic or anxiety, zero inappropriate fear. I'm likely only alive today BECAUSE of medication. The whole point behind how new medications are tested are that we often don't have a great understanding of HOW a medication works, but that doesn't matter, because it demonstrably works in some percentage of people, and for those that it doesn't work for, often another medication might. So, with zero respect because you are actively harming people, Fuck right off.
- copperx 3y ago
  Thanks for saying that. Although I've resigned myself because I know that people will often not acknowledge and have empathy and understanding towards a condition if they haven't experienced it in their own skin. It's depressing, but it seems to be part of the human condition.
- new6392689 3y ago
  [dead]
deleted 3y ago
[deleted]

ethanbond 3y ago

1. A countervailing meta-analysis does not mean it's "debunked" 2. A theory being debunked does not mean it's "just a marketing gimmick" 3. The serotonin theory being debunked does not mean "chemical imbalance" is totally exonerated Great article though, thank you for sharing. Here's the paper itself for anyone interested (AFAICT it is oddly not linked in the UCL article?): https://pubmed.ncbi.nlm.nih.gov/35854107/ https://pubmed.ncbi.nlm.nih.gov/35854107/

appleflaxen 3y ago
Great points, but the word exonerated makes no sense in that context.
- ethanbond 3y ago
  > to clear from accusation or blame Serotonin theory being debunked does not mean “chemical imbalance” is totally cleared from blame Seems clear enough to me, but noted for the future!