3 ms·

Aspirin is famous for having teratogenic effects on rabbits and would never have been approved for humans if it were to be tested nowadays

• haldujai 3y ago
  Why? Plenty of teratogenic drugs are approved and in routine use in non-pregnant patients.
  • ekianjo 3y ago
    Any recent example?
    • haldujai 3y ago
      Not really sure what you're getting at, teratogenicity only matters if a person is pregnant and lack of teratogenicity is in no way a requirement for FDA approval. There are many commonly used drugs with teratogenic risks that we discontinue in pregnancy or counsel the patient on, picking randomly from a list of medications that were approved in 2023: sparsentan I'm not sure if I'm missing something but why are you thinking teratogenicity matters when the vast majority of patients are not pregnant at a given moment?