5 ms·

This. Statins claimed to be free from adverse reactions, but it turns out that about 30% of the participants were taken out of their clinical study because of “

This. Statins claimed to be free from adverse reactions, but it turns out that about 30% of the participants were taken out of their clinical study because of “non-compliance”. However, if you dig in further, the non-compliance was because of adverse reactions. You can’t trust pharma companies if their data is secret.

TheBigSalad 3y ago
There must be more to it. Everyone who drops out is scrutinized.
anonuser123456 3y ago
If you dig further into those adverse reactions, you’ll find they are approximately equal to adverse reactions of placebo.
- Madmallard 3y ago
  Except for the part where there is a clear mechanism and cause related to muscle damage and cellular dysfunction.
  - anonuser123456 3y ago
    Show me the double blinded, placebo controlled study.
    - Madmallard 3y ago
      https://www.acc.org/about-acc/press-releases/2016/04/03/15/02/trial-offers-objective-evidence-of-muscle-related-side-effects-with-statins https://www.acc.org/about-acc/press-releases/2016/04/03/15/0... here you go anonuser123456 You will likely be able to find scientific studies toward any conclusion you want to make but there is objective evidence of this and in my own personal life significant anecdotal evidence. Given the OP title and topic and the massive reproducibility problem in medicine and perverse incentive problem in medicine, you will not be able to know the truth about the safety of medications to a high degree. It is like the reviews problem on Amazon. All medications come with studies giving 5 star reviews. But the reality is nowhere near the same. Blackbox warnings and such are all we have to place a significant ding on this problem before taking the drugs off the market for clearly causing intolerable issues in large swaths of people. This is a complex muddled issue. Argumentation with citations of 'articles' from journals likely will not lead to truthful discovery, unfortunately.
nradov 3y ago
That is medical misinformation. No drug company ever claimed that their statins were free from adverse effects. There are many statins on the market now, and patients who experience bad side effects from one will often do well on another. Getting the treatment right is a trial and error process. https://peterattiamd.com/why-a-recent-study-hasnt-shaken-my-faith-in-statins/ https://peterattiamd.com/why-a-recent-study-hasnt-shaken-my-...

TheBigSalad 3y ago

There must be more to it. Everyone who drops out is scrutinized.

anonuser123456 3y ago

If you dig further into those adverse reactions, you’ll find they are approximately equal to adverse reactions of placebo.

Madmallard 3y ago
Except for the part where there is a clear mechanism and cause related to muscle damage and cellular dysfunction.
- anonuser123456 3y ago
  Show me the double blinded, placebo controlled study.
  - Madmallard 3y ago
    https://www.acc.org/about-acc/press-releases/2016/04/03/15/02/trial-offers-objective-evidence-of-muscle-related-side-effects-with-statins https://www.acc.org/about-acc/press-releases/2016/04/03/15/0... here you go anonuser123456 You will likely be able to find scientific studies toward any conclusion you want to make but there is objective evidence of this and in my own personal life significant anecdotal evidence. Given the OP title and topic and the massive reproducibility problem in medicine and perverse incentive problem in medicine, you will not be able to know the truth about the safety of medications to a high degree. It is like the reviews problem on Amazon. All medications come with studies giving 5 star reviews. But the reality is nowhere near the same. Blackbox warnings and such are all we have to place a significant ding on this problem before taking the drugs off the market for clearly causing intolerable issues in large swaths of people. This is a complex muddled issue. Argumentation with citations of 'articles' from journals likely will not lead to truthful discovery, unfortunately.

nradov 3y ago

That is medical misinformation. No drug company ever claimed that their statins were free from adverse effects. There are many statins on the market now, and patients who experience bad side effects from one will often do well on another. Getting the treatment right is a trial and error process. https://peterattiamd.com/why-a-recent-study-hasnt-shaken-my-faith-in-statins/ https://peterattiamd.com/why-a-recent-study-hasnt-shaken-my-...