4 ms·

Those drugs are not approved for use in children and require subcutaneous injections. It would probably take more than 10 years just to push it through childre

Those drugs are not approved for use in children and require subcutaneous injections. It would probably take more than 10 years just to push it through children approval and it would fail because they are not at all side effect free especially on a growing body. I think you’re way too optimistic about drug efficacy. The studies I’ve seen on those drugs showed they were less effective then gastric bypass surgery and I’ve seen people who get that surgery and then still struggle to keep weight off. We need more government propaganda against obesity. We were able to reduce smoking with propaganda we can do the same with obesity. Problem is the majority is overweight or obese already and they’re sensitive about it. There’s even pro obesity people.

anovikov 3y ago
[flagged]
- nindalf 3y ago
  Are you suggesting that race and weight are equally immutable? Or that man-made consequences (incarceration) is the same as automatic health consequences (heart problems)?
  - ceejayoz 3y ago
    > Are you suggesting that race and weight are equally immutable? Statistically, they're pretty close. https://www.ncbi.nlm.nih.gov/books/NBK221839/ https://www.ncbi.nlm.nih.gov/books/NBK221839/ "The percentage of individuals who lose weight and successfully maintain the loss has been estimated to be as small as 1 to 3 percent." Every intervention outside of bariatric surgery and maybe these new drugs (we still need to see how those patients are doing in a decade) is virtually guaranteed to fail.
    - anovikov 3y ago
      That's exactly my point. Nearly as immutable as race.
    - anovikov 3y ago
      So sounds like, it is even more immutable than race. Because 1-3% is smaller than a ratio of people with 1/8 to 1/32 African blood, to those with >50% African blood, and those people between 1/8 and 1/32 have a fluid racial identity that depends on their circle of contacts, neighbourhood, and personal choice (see https://archive.is/uMVKL https://archive.is/uMVKL). Someone literally has a better chance at changing their race than losing weight. "Anti-obesity propaganda" is as good as KKK to alienate a large group of people, and will achieve little else.
ceejayoz 3y ago
> We were able to reduce smoking with propaganda we can do the same with obesity. Well, that, and taxing it massively, and banning its sale to children, and banning it in most spaces outside the home...
hn_throwaway_99 3y ago
> We need more government propaganda against obesity. What do you think this "government propaganda" would look like in a way that would be effective? We've been shaming people for decades about being fat and it obviously hasn't reduced obesity rates. I remember a survey from the late 90s or early 00s I think where it asked kids about different disabilities, and the majority said they'd rather lose a limb than be fat. It's only going to get worse as with the rise of smartphones and other tech in the past 15 years there is ample evidence that kids get much less physical activity then they used to.
- tekla 3y ago
  Shame even harder.
- prottog 3y ago
  > We've been shaming people for decades about being fat The shaming has been decreasing in Western societies with the "body positivity" or "health at any size" movement, if I'm not mistaken.
  - hn_throwaway_99 3y ago
    As it should be, as shaming has proven entirely ineffective, and long term, durable weight loss is extremely rare in any case. In my opinion, if people are overweight, they might as well try to deal with the issues while being happy than while being depressed. I also think it's really important to separate "body positivity" from the much rarer (and false) instances of "obesity doesn't matter for health." I associate body positivity with things like "the Richard Simmons mindset", i.e. no matter what your weight is that getting up and moving/dancing can feel great and improve your health and your mood, or the "Michelle Obama mindset", that healthy eating should start with eating fruits and vegetables rather than focus on dieting.
- hendersoon 3y ago
  It won't get worse, that was my point. These peptides work. REALLY work. They just need to get cheaper. Another poster noted that it takes much longer to approve medications for children, so my 5 year prediction may well have been wildly optimistic, but they are already approved for adults.
hendersoon 3y ago
They aren't approved /yet/, no. They do not require injections, there's a formulation already approved called Rybelsus that doesn't. Tirzepatide is roughly equivalent to gastric bypass. Most (not all) people that struggle to lose weight after gastric bypass have a psychological issue causing them to continue eating even when they feel full.

anovikov 3y ago

[flagged]

nindalf 3y ago
Are you suggesting that race and weight are equally immutable? Or that man-made consequences (incarceration) is the same as automatic health consequences (heart problems)?
- ceejayoz 3y ago
  > Are you suggesting that race and weight are equally immutable? Statistically, they're pretty close. https://www.ncbi.nlm.nih.gov/books/NBK221839/ https://www.ncbi.nlm.nih.gov/books/NBK221839/ "The percentage of individuals who lose weight and successfully maintain the loss has been estimated to be as small as 1 to 3 percent." Every intervention outside of bariatric surgery and maybe these new drugs (we still need to see how those patients are doing in a decade) is virtually guaranteed to fail.
  - anovikov 3y ago
    That's exactly my point. Nearly as immutable as race.
  - anovikov 3y ago
    So sounds like, it is even more immutable than race. Because 1-3% is smaller than a ratio of people with 1/8 to 1/32 African blood, to those with >50% African blood, and those people between 1/8 and 1/32 have a fluid racial identity that depends on their circle of contacts, neighbourhood, and personal choice (see https://archive.is/uMVKL https://archive.is/uMVKL). Someone literally has a better chance at changing their race than losing weight. "Anti-obesity propaganda" is as good as KKK to alienate a large group of people, and will achieve little else.

ceejayoz 3y ago

> We were able to reduce smoking with propaganda we can do the same with obesity. Well, that, and taxing it massively, and banning its sale to children, and banning it in most spaces outside the home...

hn_throwaway_99 3y ago

> We need more government propaganda against obesity. What do you think this "government propaganda" would look like in a way that would be effective? We've been shaming people for decades about being fat and it obviously hasn't reduced obesity rates. I remember a survey from the late 90s or early 00s I think where it asked kids about different disabilities, and the majority said they'd rather lose a limb than be fat. It's only going to get worse as with the rise of smartphones and other tech in the past 15 years there is ample evidence that kids get much less physical activity then they used to.

tekla 3y ago
Shame even harder.
prottog 3y ago
> We've been shaming people for decades about being fat The shaming has been decreasing in Western societies with the "body positivity" or "health at any size" movement, if I'm not mistaken.
- hn_throwaway_99 3y ago
  As it should be, as shaming has proven entirely ineffective, and long term, durable weight loss is extremely rare in any case. In my opinion, if people are overweight, they might as well try to deal with the issues while being happy than while being depressed. I also think it's really important to separate "body positivity" from the much rarer (and false) instances of "obesity doesn't matter for health." I associate body positivity with things like "the Richard Simmons mindset", i.e. no matter what your weight is that getting up and moving/dancing can feel great and improve your health and your mood, or the "Michelle Obama mindset", that healthy eating should start with eating fruits and vegetables rather than focus on dieting.
hendersoon 3y ago
It won't get worse, that was my point. These peptides work. REALLY work. They just need to get cheaper. Another poster noted that it takes much longer to approve medications for children, so my 5 year prediction may well have been wildly optimistic, but they are already approved for adults.

hendersoon 3y ago

They aren't approved /yet/, no. They do not require injections, there's a formulation already approved called Rybelsus that doesn't. Tirzepatide is roughly equivalent to gastric bypass. Most (not all) people that struggle to lose weight after gastric bypass have a psychological issue causing them to continue eating even when they feel full.