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From the study[0][1-pdf], the exercise routine was walking on a treadmill with adjustable gradient. The objective was to keep participants in the 50-60% heart r

From the study[0][1-pdf], the exercise routine was walking on a treadmill with adjustable gradient. The objective was to keep participants in the 50-60% heart rate range for 30 minutes, which was done by altering the gradient and speed. Including the 10 minutes warm-up and 10 minutes cool-down, this gave 4x weekly workouts of 50 minutes to the mostly 75+ year old patients. Given that the participants were screened to be low-exercise individuals beforehand, this gives some evidence that "exercise more" is a reasonable treatment for low-activity seniors experiencing cognitive decline. Because it stood out as weird to me, I want to remark that the study's participation requirements explicitly filtered out depressed patients, day-to-day impaired patients, and anyone left-handed (???). [0] https://content.iospress.com/articles/journal-of-alzheimers-disease-reports/adr220062 https://content.iospress.com/articles/journal-of-alzheimers-... [1-pdf] https://content.iospress.com/download/journal-of-alzheimers-disease-reports/adr220062?id=journal-of-alzheimers-disease-reports%2Fadr220062 https://content.iospress.com/download/journal-of-alzheimers-...

kadoban 3y ago
> Because it stood out as weird to me, I want to remark that the study's participation requirements explicitly filtered out depressed patients, day-to-day impaired patients, and anyone left-handed (???). Maybe they had an abandoned or separately condsidered for publishing test where they had people manipulate _something_, and it mattered which side it was on? Does seem weird though.
ProjectArcturis 3y ago
Some left-handed people have their brains reversed, so that language is on the right side. To avoid that as a potential complication, fMRI studies often exclude lefties.
itronitron 3y ago
>> the exercise routine was walking on a treadmill with adjustable gradient That's unfortunate as the best part of a walk is getting out and seeing the neighborhood.

kadoban 3y ago

> Because it stood out as weird to me, I want to remark that the study's participation requirements explicitly filtered out depressed patients, day-to-day impaired patients, and anyone left-handed (???). Maybe they had an abandoned or separately condsidered for publishing test where they had people manipulate _something_, and it mattered which side it was on? Does seem weird though.

ProjectArcturis 3y ago

Some left-handed people have their brains reversed, so that language is on the right side. To avoid that as a potential complication, fMRI studies often exclude lefties.

itronitron 3y ago

>> the exercise routine was walking on a treadmill with adjustable gradient That's unfortunate as the best part of a walk is getting out and seeing the neighborhood.