33 ms·

You can buy it as a "research chemical" and save money, but then the potential consequences of diy medicine and all that that entails are all on you. Hopefully

You can buy it as a "research chemical" and save money, but then the potential consequences of diy medicine and all that that entails are all on you. Hopefully the price will come down more as it becomes more prevalent or as generics become available.

rektide 3y ago
I'm not that afraid of swallowing random chemicals but self injecting is a bit hardcore for me.
- EthicalSimilar 3y ago
  FWIW, SubQ injections are pretty much completely unnoticeable in terms of pain / feeling at all. It’s more the mental barrier of doing it to yourself but once you’ve done it for the first time you soon realise it’s fine.
  - rektide 3y ago
    The actual doing it seems wild/absurd, but I don't think that would hold me back. This is ignorant/uniformed, but, taking research chemical by ingestion feels like I have some natural barriers still. Where-as I feel like there's a much more raw exposure to risk with injection. Also there's dumb risks like infection, if I don't attend well enough to injections. In spite of these protests, I think you are probably much closer to the truth here. Thanks for writing. These reactions I have are, I suspect, not really significant.
    - idontwantthis 3y ago
      Counterpoint: Don’t inject yourself with stuff you found on the internet because people on the internet told you it’s ok.
- opportune 3y ago
  Steroid users do it all the time and I haven’t heard of steroid users dealing with infections much.
  - pixl97 3y ago
    I'm sure its because most people aren't going to talk about illegal drug use and when it goes wrong.
    - opportune 3y ago
      There are tons of online places where people openly discuss steroid use like r/steroids and many oldschool phpbb-style steroid forums
scheme271 3y ago
GLP-1 agonists are a bit more tricky since they are temperature sensitive and need to be injected. You'll really need to be careful to keep it sterile and handle it properly. Whether the "research chemical" will receive the proper care until it gets into your hands is something that you're literally gambling your health on.
- reaperman 3y ago
  You ship it as a dry/lypohilized powder, both semaglutide and tirzepatide survives long China->Europe shipping in the summer just fine, with customs delays. The testing I've seen showed 99.965% purity of semaglutide after 22 days in shipping from China to Poland during April. Tirzepatide shows 99.064% purity after 58 days of shipping in October-November. These didn't start out at 100.00% purity either, so they likely experienced absolutely minimal degradation in shipment. You reconstitute it with Bacteriostatic Water which is available without a prescription in the USA and contains 0.9% benzyl alcohol to inhibit bacterial growth. If you're particularly concerned you buy a 0.22 micrometer PVDF "syringe filter" and pump it through that to another, fresh/sealed sterile vial which you can get for like $2.00 from a medical supply company (the syringe, filter, and vials are gamma-irradiated to destroy any remnants of RNA/DNA). That size filtration will filter out any lifeforms (fungal, bacterial, viral) while allowing the peptide/drug itself to pass through. So you get a guaranteed sterile solution out of the filter.
  - quazar 3y ago
    Where do you buy it from to ship to Poland?
    - reaperman 3y ago
      Anything specific would be inappropriate for this forum. But the broad answer is a chemicals distributor in China. I actually only utilize them for legal "nutritional" compounds, but others use them for pharmaceutical options, and those are independently tested frequently by a variety of stakeholders. Personally I really wish US citizens didn't feel forced to go outside of the quality protections of the FDA for their medical care.

rektide 3y ago

I'm not that afraid of swallowing random chemicals but self injecting is a bit hardcore for me.

EthicalSimilar 3y ago
FWIW, SubQ injections are pretty much completely unnoticeable in terms of pain / feeling at all. It’s more the mental barrier of doing it to yourself but once you’ve done it for the first time you soon realise it’s fine.
- rektide 3y ago
  The actual doing it seems wild/absurd, but I don't think that would hold me back. This is ignorant/uniformed, but, taking research chemical by ingestion feels like I have some natural barriers still. Where-as I feel like there's a much more raw exposure to risk with injection. Also there's dumb risks like infection, if I don't attend well enough to injections. In spite of these protests, I think you are probably much closer to the truth here. Thanks for writing. These reactions I have are, I suspect, not really significant.
  - idontwantthis 3y ago
    Counterpoint: Don’t inject yourself with stuff you found on the internet because people on the internet told you it’s ok.
opportune 3y ago
Steroid users do it all the time and I haven’t heard of steroid users dealing with infections much.
- pixl97 3y ago
  I'm sure its because most people aren't going to talk about illegal drug use and when it goes wrong.
  - opportune 3y ago
    There are tons of online places where people openly discuss steroid use like r/steroids and many oldschool phpbb-style steroid forums

scheme271 3y ago

GLP-1 agonists are a bit more tricky since they are temperature sensitive and need to be injected. You'll really need to be careful to keep it sterile and handle it properly. Whether the "research chemical" will receive the proper care until it gets into your hands is something that you're literally gambling your health on.

reaperman 3y ago
You ship it as a dry/lypohilized powder, both semaglutide and tirzepatide survives long China->Europe shipping in the summer just fine, with customs delays. The testing I've seen showed 99.965% purity of semaglutide after 22 days in shipping from China to Poland during April. Tirzepatide shows 99.064% purity after 58 days of shipping in October-November. These didn't start out at 100.00% purity either, so they likely experienced absolutely minimal degradation in shipment. You reconstitute it with Bacteriostatic Water which is available without a prescription in the USA and contains 0.9% benzyl alcohol to inhibit bacterial growth. If you're particularly concerned you buy a 0.22 micrometer PVDF "syringe filter" and pump it through that to another, fresh/sealed sterile vial which you can get for like $2.00 from a medical supply company (the syringe, filter, and vials are gamma-irradiated to destroy any remnants of RNA/DNA). That size filtration will filter out any lifeforms (fungal, bacterial, viral) while allowing the peptide/drug itself to pass through. So you get a guaranteed sterile solution out of the filter.
- quazar 3y ago
  Where do you buy it from to ship to Poland?
  - reaperman 3y ago
    Anything specific would be inappropriate for this forum. But the broad answer is a chemicals distributor in China. I actually only utilize them for legal "nutritional" compounds, but others use them for pharmaceutical options, and those are independently tested frequently by a variety of stakeholders. Personally I really wish US citizens didn't feel forced to go outside of the quality protections of the FDA for their medical care.