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How does this fit into the https://en.m.wikipedia.org/wiki/Central_dogma_of_molecular_biology https://en.m.wikipedia.org/wiki/Central_dogma_of_molecular_b... ac
by firstlink 3y ago
How does this fit into the https://en.m.wikipedia.org/wiki/Central_dogma_of_molecular_biology https://en.m.wikipedia.org/wiki/Central_dogma_of_molecular_b... according to which RNA is short-lived?
- getoffmycase 3y agoRNA is generally short lived. But specific kinds of RNA can have longer lifetimes. It’s accurate to say that RNA lifetime is extremely tightly regulated, and most of the time that means that it is short lived. Its lifetime is also extremely short compared to DNA and a high percentage of proteins.
- dekhn 3y agoThe central dogma doesn't really cover the form of RNA that is speculated to be repaired here: ribosomal RNA. The central dogma concerns mainly the transcription of DNA to mRNA, the reverse transcription of RNA back to DNA, and the translation of mRNA to protein. But over time RNA has turned up in a wide range of other activities. In this case, ribosomal RNA is the functional heart of the ribosome- the machine that translates mRNA to protein. Ribosomal RNA represents a very significant investment of resources for the cell and so if it gets damaged, the cell won't be able to make proteins as quickly, or the proteins that get made might have errors, both of which have dire effects on the cell.
- dist-epoch 3y agoEven that page acknowledges that this dogma is a simplification of reality: > Transfers of information not explicitly covered in the theory