4 ms·

I think this is a class thing coming out in the data. I don't smoke but nicotine itself helps people think clearer, sharper, it's a great thing

by aliqot 4y ago

isthisthingon99 4y ago
Foods have nicotine. Perhaps not as dense as cigarettes but still
- aliqot 4y ago
  thats where vapejuice nicotine comes from, tomato, eggplant etc
lupire 4y ago
Does nicotine help for long duration (hours) after consuming it? Also smoking has a lot of non-nicotine garbage and poison.
- aliqot 4y ago
  it has a short halflife similar to caffeine, so no, unfortunately the effects taper shortly depending on dosage and ROA
lifty 4y ago
Depends how you consume it. I assume cardio vascular health will have long term consequences on cognitive function so a lifetime of smoking might have a negative effect in thinking.
- Loveaway 4y ago
  Here's a tip: you can buy concentrated nicotine shots from vape stores, mix 10ml with 5ml ethanol and 5ml water, add a drop of menthol, and you got dirt cheap nicotine mouth spray (Nicorette sells the same thing for an arm and a leg). Purest, "healthiest" method of consumption I found. Not sure if I'd call it a great thing though. It's still addictive, and no matter what anyone says, I'm pretty sure nicotine is a mild poison. Would advise anyone to stay clear of the substance, unless you're already an addict and currently smoking/vaping/snusing, then it's a great alternative.
koverda 4y ago
Any sources on that?
- vorpalhex 4y ago
  Nicotine is a wonderful anxiolytic (anti-anxiety) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439881/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439881/ There is no evidence that I am aware of that supports it otherwise improving cognition, but for many people anxiolytics will behave like nootropics (and indeed are sometimes listed as one!)
  - guerrilla 4y ago
    Hmmmmmmmmm is that why I got much more anxious after quitting... Interesting!
    - TAKEMYMONEY 4y ago
      Those were more likely withdrawal symptoms https://www.cdc.gov/tobacco/campaign/tips/quit-smoking/7-common-withdrawal-symptoms/index.html https://www.cdc.gov/tobacco/campaign/tips/quit-smoking/7-com...
  - plusminusplus 4y ago
    ...in the 169 rats that were part of the study. It further concludes: > High doses of nicotine or repeated exposure may also promote anxiety (citing 3 studies) > low doses of nicotine have a similar effect to decrease anxiety behaviours [...] whereas high doses of nicotine promote anxiety behaviours
    - vorpalhex 4y ago
      Most drugs are dose dependent. The effects of nicotine as an anxiolytic are well known: https://pubmed.ncbi.nlm.nih.gov/12151749/ https://pubmed.ncbi.nlm.nih.gov/12151749/ Rat studies to find dose limits are a valid case for rat studies.
- 4y ago
lolinder 4y ago
Nicotine could help you think sharper in the short term while smoking still does long-term damage to the brain. This study was about smoking specifically, not nicotine consumption in general.
- deleted 4y ago
  [deleted]
- tristor 4y ago
  Luckily we have some good research on both. It turns out smoking, of /any/ substance, is a net negative for a person's health. It is unsurprising that there is long-term damage to the brain, because in the short term when you smoke you are causing a reduction in oxygenation, which no doubt has long-term effects when done repetitively, nicotine aside.
eurasiantiger 4y ago
Definitely. Lower class status is associated with smoking. It is certainly the inhaled particulate matter that is causing cognitive issues — similar associations to cognitive decline can be found with high PM2.5 exposure, irrespective of the source (industry, traffic, cooking, woodsmoke, etc).
- throwaway290 4y ago
  Or just with oral breathing in general https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228257/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228257/
- vehemenz 4y ago
  Yes, but the smoking demographic may experience higher cognitive decline in general due to other lifestyle factors not caused by inhaled particulates.
  - kaispowergoo 4y ago
    Can you elaborate on this? What other lifestyle factors involving the smoking demographic are you referencing?
    - vehemenz 4y ago
      Smoking is more prevalent on the lower end of the household income scale, so any other lifestyle factors that correlate with income (too many to list here) will contribute to poorer health outcomes for the demographic in general.
pcthrowaway 4y ago
Nicotine apparently results in higher cotinine levels (which is the marker with which they found a link with lower cognition in this study). I wonder if there's something about the effects on the brain over time that makes cognitive function worse over time, even if it's helpful in the short-term. It's also possible people are self-medicating. If you tested cognitive function on people who have been prescribed to adderall their entire lives vs. people who had not, you might find lower cognitive function in the group with ADD.. but that could also be due to the tests favouring neurotypical people.

I think this is a class thing coming out in the data. I don't smoke but nicotine itself helps people think clearer, sharper, it's a great thing

by aliqot 4y ago

I think this is a class thing coming out in the data. I don't smoke but nicotine itself helps people think clearer, sharper, it's a great thing

isthisthingon99 4y ago

Foods have nicotine. Perhaps not as dense as cigarettes but still

aliqot 4y ago
thats where vapejuice nicotine comes from, tomato, eggplant etc

lupire 4y ago

Does nicotine help for long duration (hours) after consuming it? Also smoking has a lot of non-nicotine garbage and poison.

aliqot 4y ago
it has a short halflife similar to caffeine, so no, unfortunately the effects taper shortly depending on dosage and ROA

lifty 4y ago

Depends how you consume it. I assume cardio vascular health will have long term consequences on cognitive function so a lifetime of smoking might have a negative effect in thinking.

Loveaway 4y ago
Here's a tip: you can buy concentrated nicotine shots from vape stores, mix 10ml with 5ml ethanol and 5ml water, add a drop of menthol, and you got dirt cheap nicotine mouth spray (Nicorette sells the same thing for an arm and a leg). Purest, "healthiest" method of consumption I found. Not sure if I'd call it a great thing though. It's still addictive, and no matter what anyone says, I'm pretty sure nicotine is a mild poison. Would advise anyone to stay clear of the substance, unless you're already an addict and currently smoking/vaping/snusing, then it's a great alternative.

koverda 4y ago

Any sources on that?

vorpalhex 4y ago
Nicotine is a wonderful anxiolytic (anti-anxiety) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439881/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439881/ There is no evidence that I am aware of that supports it otherwise improving cognition, but for many people anxiolytics will behave like nootropics (and indeed are sometimes listed as one!)
- guerrilla 4y ago
  Hmmmmmmmmm is that why I got much more anxious after quitting... Interesting!
  - TAKEMYMONEY 4y ago
    Those were more likely withdrawal symptoms https://www.cdc.gov/tobacco/campaign/tips/quit-smoking/7-common-withdrawal-symptoms/index.html https://www.cdc.gov/tobacco/campaign/tips/quit-smoking/7-com...
- plusminusplus 4y ago
  ...in the 169 rats that were part of the study. It further concludes: > High doses of nicotine or repeated exposure may also promote anxiety (citing 3 studies) > low doses of nicotine have a similar effect to decrease anxiety behaviours [...] whereas high doses of nicotine promote anxiety behaviours
  - vorpalhex 4y ago
    Most drugs are dose dependent. The effects of nicotine as an anxiolytic are well known: https://pubmed.ncbi.nlm.nih.gov/12151749/ https://pubmed.ncbi.nlm.nih.gov/12151749/ Rat studies to find dose limits are a valid case for rat studies.
4y ago

lolinder 4y ago

Nicotine could help you think sharper in the short term while smoking still does long-term damage to the brain. This study was about smoking specifically, not nicotine consumption in general.

deleted 4y ago
[deleted]
tristor 4y ago
Luckily we have some good research on both. It turns out smoking, of /any/ substance, is a net negative for a person's health. It is unsurprising that there is long-term damage to the brain, because in the short term when you smoke you are causing a reduction in oxygenation, which no doubt has long-term effects when done repetitively, nicotine aside.

eurasiantiger 4y ago

Definitely. Lower class status is associated with smoking. It is certainly the inhaled particulate matter that is causing cognitive issues — similar associations to cognitive decline can be found with high PM2.5 exposure, irrespective of the source (industry, traffic, cooking, woodsmoke, etc).

throwaway290 4y ago
Or just with oral breathing in general https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228257/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228257/
vehemenz 4y ago
Yes, but the smoking demographic may experience higher cognitive decline in general due to other lifestyle factors not caused by inhaled particulates.
- kaispowergoo 4y ago
  Can you elaborate on this? What other lifestyle factors involving the smoking demographic are you referencing?
  - vehemenz 4y ago
    Smoking is more prevalent on the lower end of the household income scale, so any other lifestyle factors that correlate with income (too many to list here) will contribute to poorer health outcomes for the demographic in general.

pcthrowaway 4y ago

Nicotine apparently results in higher cotinine levels (which is the marker with which they found a link with lower cognition in this study). I wonder if there's something about the effects on the brain over time that makes cognitive function worse over time, even if it's helpful in the short-term. It's also possible people are self-medicating. If you tested cognitive function on people who have been prescribed to adderall their entire lives vs. people who had not, you might find lower cognitive function in the group with ADD.. but that could also be due to the tests favouring neurotypical people.