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Type 2 diabetes is strongly associated with being overweight, and it it is well-known that weight loss can reverse it, so my first thought was “how did they con
by Someone 4y ago
Type 2 diabetes is strongly associated with being overweight, and it it is well-known that weight loss can reverse it, so my first thought was “how did they control for weight loss?”.
From what I can find online, I’m. It convinced they did that. https://pubmed.ncbi.nlm.nih.gov/36515429/ https://pubmed.ncbi.nlm.nih.gov/36515429/ says:
“The mean body weight of participants in the CMNT group was reduced by 5.93 kg (SD 2.47) compared to 0.27 kg (1.43) in the control group”
I also found https://www.sciencemediacentre.org/expert-reaction-to-study-looking-at-intermittent-fasting-and-type-2-diabetes/ https://www.sciencemediacentre.org/expert-reaction-to-study-..., which says (cherry-picking a bit rom that page, but IMO, that’s not a problem for this argument):
“This is a relatively small study and the main problem is that weight loss was much greater in those allocated to intermittent fasting. This is not surprising but a proper comparison would be with individuals who reduced their food intake uniformly over time to the same degree as those doing intermittent fasting. The bottom line is that if obese/overweight persons with diabetes lose substantial amounts of weight their diabetes is likely to go into remission. This study does not show that intermittent fasting is superior to uniform caloric restriction.“
and
“So, this study did not compare two diets with the same energy intake as the intermittent diet was about 75% of energy intake compared to normal intake. Therefore there is no surprise that the intermittent diet group lost weight (almost 6kg on average or about 10% of starting body weight). As one of the best predictors of achieving remission in type 2 diabetes is weight loss, it is impossible to say if it is intermittent fasting which is helping to induce remission as it is most likely to be the result of the weight loss”
(It surprised me to read “almost 6kg on average or about 10% of starting body weight”. I know not all Chinese are large, but 60kg and (from the pubmed link “body mass index (BMI) of 19.1 to 30.4”?)
Because of that, I doubt the conclusion is correct, and it wasn’t the intermittent fasting but the weight loss that was the main factor.
(That page also gives some info about the experiment:
“for five days people ate only 840kcal per day and for the following 10 days they ate according to their appetite following the Chinese dietary guidelines for a total of 3 months”)
- wink 4y ago6kg less doesn't sound like enough to provoke such a strong reaction though? I mean, just as a total layman who is regularly gaining and losing about 5 kg, I can't imagine that would be enough to trigger getting or losing the type 2 Diabetes...
- Someone 4y agoI would guess you’re a bit larger than the average subject in this study. If the links I found are correct, the subjects in this study on average weighed 60kg and had BMIs in the range 19.1 to 30.4. If you’re 60kg and have a BMI of 25, you must be √(60/25) m tall. That’s 1.55m.