3 ms·
> SLYM is immunophenotypically distinct from the other meningeal layers in the human and mouse brain and represents a tight barrier for solutes of more than 3 k
by unsupp0rted 4y ago
> SLYM is immunophenotypically distinct from the other meningeal layers in the human and mouse brain and represents a tight barrier for solutes of more than 3 kilodaltons, effectively subdividing the subarachnoid space into two different compartments. SLYM is the host for a large population of myeloid cells, the number of which increases in response to inflammation and aging, so this layer represents an innate immune niche ideally positioned to surveil the cerebrospinal fluid.
- samstave 4y agoI learned a whole bunch of new words from you, thank you. may you please unpack this sentence, as I dont know exactly it means: >ideally positioned to surveil the cerebrospinal fluid.
- hirenj 4y agoThe immune system needs to sample and test whatever is in the cerebrospinal fluid so that it knows when to activate.
- deleted 4y ago[deleted]