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I was thinking of MALDI-TOF mass spectrometry devices used in Protiomics research. It’s a bit out of my field but I think it’s an improvement to HPLC.
by cjbgkagh 4y ago
I was thinking of MALDI-TOF mass spectrometry devices used in Protiomics research. It’s a bit out of my field but I think it’s an improvement to HPLC.
- dekhn 4y agoProbably GC-MS? https://en.wikipedia.org/wiki/Gas_chromatography%E2%80%93mass_spectrometry https://en.wikipedia.org/wiki/Gas_chromatography%E2%80%93mas... Dunno how that would isolate the sample, rather than just analyzing it though
- cjbgkagh 4y agoI’m not involved in the process of acquiring the ‘omics data. I just analyze it and read papers from other people analyzing it. I think MALDI-TOF is the gold standard for proteomics.
- rolph 4y agomass based deflection and deposition. isolation,and analysis are two different activities, many instruments are capable of both modalities, depending on technique. the problem is selecting a procedure that will not induce confounding artefacts of chemical, or physical interaction w the subject molecular entity.