5 ms·
So if it is detected, can it be reversed?
by tiku 4y ago
So if it is detected, can it be reversed?
- BaculumMeumEst 4y agothe article suggests not at this time
- melling 4y agoAt some point, it’s simply a matter of research, right? Having a longer window provides more opportunities to study the disease and for treatments
- ekianjo 4y agowe dont even know if they are actually involved in causing the impairment, but you can bet thats what big pharma will try to sell you 20 years ahead of old age.
- sokoloff 4y agoIf there's plausible (lower standard than credible) connection, I'll be happy to take their pills for 20 years after seeing the long declines brought about by Alzheimer's in several older people that I knew well.
- vidarh 4y agoI'd even be prepared to take drugs with a not unsubstantial risk of shortening my life expectancy if there was a plausible connection, after having seen both my grandmother's effectively being gone because of Alzheimer's for a decade before they physically died.
- ekianjo 4y agoYou can imagine that proving the efficacy of the drug over dozens of years is going to be especially challenging. No clinical trial ever does that.
- nradov 4y agoAnd what if those pills come with serious side effects, as most do?
- ekianjo 4y agoTaking pills for 20 years has a financial cost, and drugs typically cause side effects anyway (you dont have efficacy for free). That sounds like a bad calculation.
- hammock 4y agoReversing “it” is not necessarily the goal, the goal is holding off Alzheimer’s. Diet, sleep and exercise are lifestyle remedies that may achieve this, and pre screening for risk might provide additional motivation
- sinenomine 4y agoChronic diseases break our medical R&D model and our society is prone to normalizing these as if they were some immutable constants of life. Without reconsidering our attitude to research & development & incentives, and corresponding massively increased efforts the favorable outcome is unlikely here. If you are interested, read this FAQ: https://www.fightaging.org/faq https://www.fightaging.org/faq In my opinion we should use AI/AGI, high-throughput methods and massive clinical trials on volunteers to accelerate the medical R&D as much as possible.
- nradov 4y agoMassive clinical trials cost billions of dollars. Where will the funding come from? AI technology can't do much to cut the cost of clinical trials.