There's even software that can adapt that DDC brightness automatically using the ambient light around you. I develop Lunar (https://lunar.fyi https://lunar.fyi)

There's even software that can adapt that DDC brightness automatically using the ambient light around you. I develop Lunar (https://lunar.fyi https://lunar.fyi) that can do that for macOS. For me, the screens I use are always at the brightness where white regions are as comfortable as a piece of paper. Sure, colors aren't reproduced "as the artist/developer wanted" at those values, but neither do I need that, nor do we have e-ink screens that can reproduce color more accurately. I just want to create software, research stuff on the internet, arrange my music etc. and if I feel like doing that for 10 hours straight, I only want the screen to tire my eyes as little as possible. I also read a lot of books and research material, both on Kindle and paper. My eyes get tired after hours of doing that as well. Light is not the only factor. So although it's good to try to be optimal about the light that gets in your eyes over large periods of time, it's best to also try periodic rest and moving some activities to non-screen mediums instead of fretting endlessly over the last 5% of screen light optimization.