5 ms·

That's a roller coaster for this drug; Started off as high blood pressure candidate, ends up at Alzheimer's candidate (with a detour in the middle of course).

by ajaimk 4y ago

Scoundreller 4y ago
Don’t forget about it’s longer acting cousin (tadalafil) working for prostate problems. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054509/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054509/ Sildenafil is used for pulmonary hypertension, oddly after it’s approval for erectile dysfunction. I guess that’s a home run? And let’s not forget, Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies.
- arcticbull 4y ago
  > And let’s not forget, Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies. Overseas pharmacies like RX Limited, the one run by Paul Le Roux. [1] [1] https://en.wikipedia.org/wiki/Paul_Le_Roux https://en.wikipedia.org/wiki/Paul_Le_Roux
- raverbashing 4y ago
  > Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies. Hah I wonder if anyone has measured the size of those "markets"
  - arcticbull 4y ago
    Prosecutors have, from time to time. Le Roux's RX Limited in particular was running hundreds of millions of dollars per year. [1] Some estimates put his take at $400M total. [2] I bet Ratliff has some specific estimates in Mastermind. [1] https://www.dw.com/en/from-programmer-to-gangster-boss-the-unbelievable-story-of-paul-le-roux/a-54047877 https://www.dw.com/en/from-programmer-to-gangster-boss-the-u... [2] https://www.startribune.com/how-minnesota-agents-helped-find-paul-le-roux-and-how-the-mastermind-may-again-find-freedom/368736611/ https://www.startribune.com/how-minnesota-agents-helped-find...
    - Scoundreller 4y ago
      $500m settled by Google for ads from “Canadian” pharmacies (many of which weren’t actually in Canada). Chump change for Google when they settled it, but basically free venture capital when they booked it as revenue: https://amp.theguardian.com/technology/2011/aug/24/google-settles-us-drug-advertising-case https://amp.theguardian.com/technology/2011/aug/24/google-se...

That's a roller coaster for this drug; Started off as high blood pressure candidate, ends up at Alzheimer's candidate (with a detour in the middle of course).

by ajaimk 4y ago

That's a roller coaster for this drug; Started off as high blood pressure candidate, ends up at Alzheimer's candidate (with a detour in the middle of course).

Scoundreller 4y ago

Don’t forget about it’s longer acting cousin (tadalafil) working for prostate problems. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054509/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054509/ Sildenafil is used for pulmonary hypertension, oddly after it’s approval for erectile dysfunction. I guess that’s a home run? And let’s not forget, Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies.

arcticbull 4y ago
> And let’s not forget, Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies. Overseas pharmacies like RX Limited, the one run by Paul Le Roux. [1] [1] https://en.wikipedia.org/wiki/Paul_Le_Roux https://en.wikipedia.org/wiki/Paul_Le_Roux
raverbashing 4y ago
> Google wouldn’t be where it is today without all the ads it sold for “natural” viagra from overseas pharmacies. Hah I wonder if anyone has measured the size of those "markets"
- arcticbull 4y ago
  Prosecutors have, from time to time. Le Roux's RX Limited in particular was running hundreds of millions of dollars per year. [1] Some estimates put his take at $400M total. [2] I bet Ratliff has some specific estimates in Mastermind. [1] https://www.dw.com/en/from-programmer-to-gangster-boss-the-unbelievable-story-of-paul-le-roux/a-54047877 https://www.dw.com/en/from-programmer-to-gangster-boss-the-u... [2] https://www.startribune.com/how-minnesota-agents-helped-find-paul-le-roux-and-how-the-mastermind-may-again-find-freedom/368736611/ https://www.startribune.com/how-minnesota-agents-helped-find...
  - Scoundreller 4y ago
    $500m settled by Google for ads from “Canadian” pharmacies (many of which weren’t actually in Canada). Chump change for Google when they settled it, but basically free venture capital when they booked it as revenue: https://amp.theguardian.com/technology/2011/aug/24/google-settles-us-drug-advertising-case https://amp.theguardian.com/technology/2011/aug/24/google-se...