5 ms·

Worth noting that these are self-reported symptoms. Very large sample size and effect size, but testing 62 symptoms could yield some green jellybeans.

hajile 4y ago
- throwaway290 4y ago
  This article is about long COVID, while your comment is about vaccines. What's the relation? Otherwise it seems completely off topic. Do you imply vaccines cause long COVID? Any evidence of that?
  - helloworld11 4y ago
    Really? HN comments are full of tangents that only partly relate to an original post's topic, and it makes them all the more interesting in general. The comment above is talking about COVID vaccines with interesting links and a decent argument, in a post about long covid and its effects. There's plenty of conversation-worthy correlation between the two.
    - throwaway290 4y ago
      I'm on HN for a decade at least, it is always either clear how a comment relates to the subject or it explicitly declares it's off-topic which is fine as well
  - hajile 4y ago
    Yes, there are some studies indicating that vaccines may cause long covid. This of course raises the interesting question about where vaccine reactions end and long covid begins. https://www.science.org/content/article/rare-cases-coronavirus-vaccines-may-cause-long-covid-symptoms https://www.science.org/content/article/rare-cases-coronavir... https://pubmed.ncbi.nlm.nih.gov/35084966/ https://pubmed.ncbi.nlm.nih.gov/35084966/ Further, the vaccine is associated with lengthened menstrual cycle times in women. Some have conjectured this is due to the Lipid Nano-particles from the vaccine coalescing into the ovaries and to a lesser extent in the testes (as happened in Pfizer mice trial data released earlier this year and was opposite of their public statements about those particles staying in the muscle tissue around the injection site). Combining the two raises the question about if that is a spurious correlation and the actual cause is the spike protein itself. https://www.cidrap.umn.edu/news-perspective/2022/09/study-finds-slightly-longer-menstrual-cycle-after-covid-vaccine https://www.cidrap.umn.edu/news-perspective/2022/09/study-fi...
    - throwaway290 4y ago
      > Yes, there are some studies indicating that vaccines may cause long covid You linked one study to be precise, which is about "rare cases". So going off that into vaccine alarmism and calling this vaccine rollout only better than a rollout that paralysed half a million children (and so I assume worse than a rollout that may have created AIDS?) is a bit disingenuous. > Further, the vaccine is associated with lengthened menstrual cycle times in women. I'm aware... Still not long COVID.
      - hajile 4y ago
        We have basically three causal options on vaccine reactions assuming you believe the CDC and doctors who admitted patients to the hospital. 1. The vaccine mRNA code is buggy and has side effects beyond the spike protein it creates. 2. The vaccine lipid nano-particles are causing side effects in addition to the spike protein. 3. We don't fully understand the effects of the spike protein and most or all of the vaccine side effects are actually associated with the virus spike. If it's case 1 or 2, then the vaccine is simply bad. If it's case 3, then vaccine side effects are actually analogous to long covid. The third case is the least "alarmist" take of the three. In the third case, the only issue with the article in question is quantity and not counting enough of these side effects in their long covid analysis.
        throwaway290 4y ago
        And this relates to long COVID how? Maybe you should post this as a story rather than hijacking comment thread of another story..
- megous 4y ago
  Finally some interesting data. Already downloading... :)
  - megous 4y ago
    Interesting, looks like it has enough information to track individual people's symptoms over time. Perfect. And there are a lot of check-in timepoints per registrant (144 mil. time points, 9 mil. registrants)
- staticman2 4y ago
  The word "vaccine" appears nowhere in the linked article. As for your off topic post, if you were concerned with the data I would think your first step would be to verify if the data was real. Your second step would be to understand the context in which the data was collected and reported. Your third step would probably be to attempt to establish a baseline of how many reports we'd expect if the vaccine were a placebo. Even one of those anti-vaccer web sites has a disclaimer that says "Reports are not proof of causality." Which seems to hint that you misunderstand what the data is reporting.
  - hajile 4y ago
biztos 4y ago
Probable “green jellybean” reference: https://xkcd.com/882/ https://xkcd.com/882/

hajile 4y ago

throwaway290 4y ago
This article is about long COVID, while your comment is about vaccines. What's the relation? Otherwise it seems completely off topic. Do you imply vaccines cause long COVID? Any evidence of that?
- helloworld11 4y ago
  Really? HN comments are full of tangents that only partly relate to an original post's topic, and it makes them all the more interesting in general. The comment above is talking about COVID vaccines with interesting links and a decent argument, in a post about long covid and its effects. There's plenty of conversation-worthy correlation between the two.
  - throwaway290 4y ago
    I'm on HN for a decade at least, it is always either clear how a comment relates to the subject or it explicitly declares it's off-topic which is fine as well
- hajile 4y ago
  Yes, there are some studies indicating that vaccines may cause long covid. This of course raises the interesting question about where vaccine reactions end and long covid begins. https://www.science.org/content/article/rare-cases-coronavirus-vaccines-may-cause-long-covid-symptoms https://www.science.org/content/article/rare-cases-coronavir... https://pubmed.ncbi.nlm.nih.gov/35084966/ https://pubmed.ncbi.nlm.nih.gov/35084966/ Further, the vaccine is associated with lengthened menstrual cycle times in women. Some have conjectured this is due to the Lipid Nano-particles from the vaccine coalescing into the ovaries and to a lesser extent in the testes (as happened in Pfizer mice trial data released earlier this year and was opposite of their public statements about those particles staying in the muscle tissue around the injection site). Combining the two raises the question about if that is a spurious correlation and the actual cause is the spike protein itself. https://www.cidrap.umn.edu/news-perspective/2022/09/study-finds-slightly-longer-menstrual-cycle-after-covid-vaccine https://www.cidrap.umn.edu/news-perspective/2022/09/study-fi...
  - throwaway290 4y ago
    > Yes, there are some studies indicating that vaccines may cause long covid You linked one study to be precise, which is about "rare cases". So going off that into vaccine alarmism and calling this vaccine rollout only better than a rollout that paralysed half a million children (and so I assume worse than a rollout that may have created AIDS?) is a bit disingenuous. > Further, the vaccine is associated with lengthened menstrual cycle times in women. I'm aware... Still not long COVID.
    - hajile 4y ago
      We have basically three causal options on vaccine reactions assuming you believe the CDC and doctors who admitted patients to the hospital. 1. The vaccine mRNA code is buggy and has side effects beyond the spike protein it creates. 2. The vaccine lipid nano-particles are causing side effects in addition to the spike protein. 3. We don't fully understand the effects of the spike protein and most or all of the vaccine side effects are actually associated with the virus spike. If it's case 1 or 2, then the vaccine is simply bad. If it's case 3, then vaccine side effects are actually analogous to long covid. The third case is the least "alarmist" take of the three. In the third case, the only issue with the article in question is quantity and not counting enough of these side effects in their long covid analysis.
      - throwaway290 4y ago
        And this relates to long COVID how? Maybe you should post this as a story rather than hijacking comment thread of another story..
megous 4y ago
Finally some interesting data. Already downloading... :)
- megous 4y ago
  Interesting, looks like it has enough information to track individual people's symptoms over time. Perfect. And there are a lot of check-in timepoints per registrant (144 mil. time points, 9 mil. registrants)
staticman2 4y ago
The word "vaccine" appears nowhere in the linked article. As for your off topic post, if you were concerned with the data I would think your first step would be to verify if the data was real. Your second step would be to understand the context in which the data was collected and reported. Your third step would probably be to attempt to establish a baseline of how many reports we'd expect if the vaccine were a placebo. Even one of those anti-vaccer web sites has a disclaimer that says "Reports are not proof of causality." Which seems to hint that you misunderstand what the data is reporting.
- hajile 4y ago

biztos 4y ago

Probable “green jellybean” reference: https://xkcd.com/882/ https://xkcd.com/882/