12 ms·
Here is the link to the actual study: https://www.nature.com/articles/s41467-022-33415-5 https://www.nature.com/articles/s41467-022-33415-5 One thing that imm
by timr 4y ago
Here is the link to the actual study:
https://www.nature.com/articles/s41467-022-33415-5 https://www.nature.com/articles/s41467-022-33415-5
One thing that immediately leaps out to me is that the profile of "symptoms" is broadly similar between "never infected" and "symptomatic infected" groups, but completely different (much lower across the board) for "asymptomatic infected":
https://www.nature.com/articles/s41467-022-33415-5/tables/2 https://www.nature.com/articles/s41467-022-33415-5/tables/2
There does seem to be elevation vs. controls for certain symptoms (including a few that are mechanistically believable, such as shortness of breath), but because this is self-reported data, it's still hopelessly biased. People who self-identify as sick are going to be more likely to report symptoms than those who do not...which is probably why we see the much lower rates of "long covid" symptoms in the asymptomatic infection group.
At the very least, this should make you question the idea of "long covid" after asymptomatic infection. Based on this data, "long covid" is closer to the symptom profile seen in people who were never infected at all than it is to the symptom profile of people who knew they were infected, but didn't have primary illness.