3 ms·

What are you basing this estimate on? From the article, it sounds like funding is scant: > Koralnik complains that no government money has been earmarked speci

What are you basing this estimate on? From the article, it sounds like funding is scant: > Koralnik complains that no government money has been earmarked specifically for research into long COVID’s significant neurological manifestations, and that the NIH hasn’t assigned a neurologist to review such grant applications. “Therefore, it’s been very difficult, if not impossible, to get funded for the research for neuro-COVID,” he says. Would difficulty getting funding bias early prevalence estimates?

cjbgkagh 4y ago
I think the numbers in this article are overstated but are within the ballpark. Covid isn’t the only virus to cause ME/CFS and it isn’t even the worst. MERS is worse and was studied extensively. It requires a genetic predisposition that appears to only exist in 10% of people. Within that 10% there is a spectrum of severity with half recovering. Unfortunately as someone with the gene mutation for hEDS I’m extremely susceptible to it and do indeed have ME/CFS (predating covid) which to me is largely indistinguishable from LongCovid. I have a strong personal stake and have extensively researched it.
- AstralStorm 4y ago
  Well, Long Covid is prpbably a worse version of it as it apparently can for reservoirs in susceptible people. So not only are they immune dysregulated, but also sick repeatedly...
  - cjbgkagh 4y ago
    Many viruses hide in reservoirs. EBV is famous for reactivating. ME/CFS appears to be a threshold condition where once you pass a threshold you enter a diseased state and it’s a crapshoot to how bad it gets. From what I’ve seen LongCovid is not worse than ordinary ME/CFS, it appears to be exactly the same.
  - nradov 4y ago
    That is highly speculative. Severely immunocompromised patients can experience persistent SARS-CoV-2 infections lasting months, but otherwise there is no reliable evidence of such reservoirs. Coronaviruses don't stick around like, for example, herpesviruses.

cjbgkagh 4y ago

I think the numbers in this article are overstated but are within the ballpark. Covid isn’t the only virus to cause ME/CFS and it isn’t even the worst. MERS is worse and was studied extensively. It requires a genetic predisposition that appears to only exist in 10% of people. Within that 10% there is a spectrum of severity with half recovering. Unfortunately as someone with the gene mutation for hEDS I’m extremely susceptible to it and do indeed have ME/CFS (predating covid) which to me is largely indistinguishable from LongCovid. I have a strong personal stake and have extensively researched it.

AstralStorm 4y ago
Well, Long Covid is prpbably a worse version of it as it apparently can for reservoirs in susceptible people. So not only are they immune dysregulated, but also sick repeatedly...
- cjbgkagh 4y ago
  Many viruses hide in reservoirs. EBV is famous for reactivating. ME/CFS appears to be a threshold condition where once you pass a threshold you enter a diseased state and it’s a crapshoot to how bad it gets. From what I’ve seen LongCovid is not worse than ordinary ME/CFS, it appears to be exactly the same.
- nradov 4y ago
  That is highly speculative. Severely immunocompromised patients can experience persistent SARS-CoV-2 infections lasting months, but otherwise there is no reliable evidence of such reservoirs. Coronaviruses don't stick around like, for example, herpesviruses.