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Any infection you have will deplete one nutrient or another, and if you have a genetic susceptibility, this depletion might be much greater than someone else. T

Any infection you have will deplete one nutrient or another, and if you have a genetic susceptibility, this depletion might be much greater than someone else. To correct these nutrition depletion to keep these viruses in check, you will need to take mega doses of the supplement for a short period. If you are still one of these people that think zinc does not play a role in COVID outcomes I have nothing left to say but: By destroying the ACE2 receptor, SARS2 causes a depletion of zinc since zinc makes up the structure of ACE2 and prevents the recycling of zinc in the cell. https://www.sciencedirect.com/science/article/pii/S120197122030730X https://www.sciencedirect.com/science/article/pii/S120197122... https://www.nature.com/articles/s41467-020-18880-0 https://www.nature.com/articles/s41467-020-18880-0 And hey and guess what. They find that people with zinc deficiency have more herpes out breaks! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283972/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283972/ Why? Because the same thing happens with herpes but with NECTIN1 receptor and ADAM10. Low zinc means less ADAM10 activity and more NECTIN1 on the cell and therefor more herepes virus replication. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906284/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906284/ So what might be happening with the low cortisol they speak of in the study? ACE2 is all over the adrenal gland, and when ACE2 is destroyed the adrenal gland shuts down and cannot release as much cortisol. https://www.frontiersin.org/articles/10.3389/fendo.2020.593179/full https://www.frontiersin.org/articles/10.3389/fendo.2020.5931... Now, many of you will come back as show me all the studies that reveal that zinc actually reduces cortisol. And I agree, but do you know why? When someone is not zinc deficiency, adding more zinc will trigger ADAM17 to cleave ACE2 off the cell and create Soluble ACE2. Zinc the ACE2 is not on the adrenal gland anymore cortisol will not be released. https://www.mdpi.com/viruses/viruses-12-00491/article_deploy/html/images/viruses-12-00491-g001.png https://www.mdpi.com/viruses/viruses-12-00491/article_deploy... But in a zinc deficient state there is not enough ACE2 to start with and ADAM17 activity is also low. By taking zinc and correcting the deficiency you will increase activity for both ACE2 and ADAM17. If you know someone or if you have long covid, I highly suggest that you at least get your serum zinc levels tested.

nums 4y ago
Great comment. From prior research, the hormonal interactions around the thyroid and immune system are complex. You've boiled it down fairly well here as related to zinc. Wasn't there some discussion about hydroxychloroquine being effectively only in conjunction with zinc as the hydroxychloroquine encourages cellular uptake of zinc. Ergo, zinc is the key ingredient. Further, I seem to recall the book "The end of alzheimer's" (high recommend) talked alot about zinc wrt neurological health.
amelius 4y ago
If only it were that simple. How many long covid patients have already tried multivitamin/mineral supplements out of despair?
- FollowingTheDao 4y ago
  How many people do you know have tried it? How many clinical studies have there been on this? How many people have tried it And it worked? How many people know that it might take up to 240 mg of zinc sulfate for a week to correct this? How many people are taking way too small doses of any of the supplements to make a difference? The fact that it is the simple is what is causing people to overlook it as a possibility. If you can come up with a better sourced reason why this is happening to people I’d be interested to hear it. There’s nothing in the material I presented that is false. But yet you can’t believe it.

nums 4y ago

Great comment. From prior research, the hormonal interactions around the thyroid and immune system are complex. You've boiled it down fairly well here as related to zinc. Wasn't there some discussion about hydroxychloroquine being effectively only in conjunction with zinc as the hydroxychloroquine encourages cellular uptake of zinc. Ergo, zinc is the key ingredient. Further, I seem to recall the book "The end of alzheimer's" (high recommend) talked alot about zinc wrt neurological health.

amelius 4y ago

If only it were that simple. How many long covid patients have already tried multivitamin/mineral supplements out of despair?

FollowingTheDao 4y ago
How many people do you know have tried it? How many clinical studies have there been on this? How many people have tried it And it worked? How many people know that it might take up to 240 mg of zinc sulfate for a week to correct this? How many people are taking way too small doses of any of the supplements to make a difference? The fact that it is the simple is what is causing people to overlook it as a possibility. If you can come up with a better sourced reason why this is happening to people I’d be interested to hear it. There’s nothing in the material I presented that is false. But yet you can’t believe it.