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To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and fo

To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and for asking a question that must be on many people’s minds: can monoclonal antibody administration promote resistance analogous to bacterial antibiotic resistance? Be aware that live virus vaccines are certainly not monoclonal antibody injections. As well, rather than spending your mental energy developing excuses to dismiss, why not think on the subject at hand? You should wonder why this mouse model produces broadly neutralizing antibodies in response to COVID spike proteins while the human immune system does not. That’s a bit interesting to the subject of COVID, isn’t it? Certainly more so than windmills and politics.

johnchristopher 4y ago
> To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and for asking a question that must be on many people’s minds: can monoclonal antibody administration promote resistance analogous to bacterial antibiotic resistance? No, I am singling out another comment which spreads doubts and denial by hiding them among good faith arguments. For instance: > (that the successive COVID variants have proven less debilitating and deadly) Doesn't mean it's not debilitating and deadly. > basically everyone I know has been infected now. And I haven't and neither my best friend nor my parents did. But my brother did and another friend did. Guess which one is complaining 6 months later of symptoms that are not going away ? > As well, rather than spending your mental energy developing excuses to dismiss, why not think on the subject at hand? You should wonder why this mouse model produces broadly neutralizing antibodies in response to COVID spike proteins while the human immune system does not. > That’s a bit interesting to the subject of COVID, isn’t it? Certainly more so than windmills and politics. I believe Covid was and is still dangerous and not to be taken lightly because "most people I know has been infected and successive strains are less deadly" (the last one being also dodgy since it might as well be less deadly for an individual but more deadly for a population if it infects much more people, anyway...). That's as worthy to discuss as the core of the submission is.
- jjcon 4y ago
  > by hiding them among good faith arguments It is literally in the HN rules that you are supposed to assume good faith, not concoct false attributions of intent and conspiracy. I did not intend to hide anything, I was earnestly asking a question (clearly shared by plenty others in this post). It should not upset you this much. I apologize for anything triggering to you that I said, that wasn't my intent. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
  - johnchristopher 4y ago
    > It should not upset you this much. The question pertaining to the core of the submission does not upset me, nor do I find it in bad faith (that one I assume good faith since it's legitimate). > Current Covid strains don’t seem all that bad, basically everyone I know has been infected now. This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question. > I apologize for anything triggering and > Assume good faith - its in the rules friend (https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html) This wording (emphasis mine) tells me all there is to know about why I shouldn't explain myself to you.
    - cas14655 4y ago
      > This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question. Question: how low does the IFR have to be so we can call a disease "not so bad" without "minimizing" it?
      - johnchristopher 4y ago
        Question: how long does it take for that other famous disease to show the long term effects of t-cells exhaustion ?
        cas14655 4y ago

johnchristopher 4y ago

> To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and for asking a question that must be on many people’s minds: can monoclonal antibody administration promote resistance analogous to bacterial antibiotic resistance? No, I am singling out another comment which spreads doubts and denial by hiding them among good faith arguments. For instance: > (that the successive COVID variants have proven less debilitating and deadly) Doesn't mean it's not debilitating and deadly. > basically everyone I know has been infected now. And I haven't and neither my best friend nor my parents did. But my brother did and another friend did. Guess which one is complaining 6 months later of symptoms that are not going away ? > As well, rather than spending your mental energy developing excuses to dismiss, why not think on the subject at hand? You should wonder why this mouse model produces broadly neutralizing antibodies in response to COVID spike proteins while the human immune system does not. > That’s a bit interesting to the subject of COVID, isn’t it? Certainly more so than windmills and politics. I believe Covid was and is still dangerous and not to be taken lightly because "most people I know has been infected and successive strains are less deadly" (the last one being also dodgy since it might as well be less deadly for an individual but more deadly for a population if it infects much more people, anyway...). That's as worthy to discuss as the core of the submission is.

jjcon 4y ago
> by hiding them among good faith arguments It is literally in the HN rules that you are supposed to assume good faith, not concoct false attributions of intent and conspiracy. I did not intend to hide anything, I was earnestly asking a question (clearly shared by plenty others in this post). It should not upset you this much. I apologize for anything triggering to you that I said, that wasn't my intent. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
- johnchristopher 4y ago
  > It should not upset you this much. The question pertaining to the core of the submission does not upset me, nor do I find it in bad faith (that one I assume good faith since it's legitimate). > Current Covid strains don’t seem all that bad, basically everyone I know has been infected now. This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question. > I apologize for anything triggering and > Assume good faith - its in the rules friend (https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html) This wording (emphasis mine) tells me all there is to know about why I shouldn't explain myself to you.
  - cas14655 4y ago
    > This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question. Question: how low does the IFR have to be so we can call a disease "not so bad" without "minimizing" it?
    - johnchristopher 4y ago
      Question: how long does it take for that other famous disease to show the long term effects of t-cells exhaustion ?
      - cas14655 4y ago