3 ms·
Raleigh's criterion says hydrogens should be just on the cusp, at least with home source xrays. Not sure about synchotron.
by COGlory 4y ago
Raleigh's criterion says hydrogens should be just on the cusp, at least with home source xrays. Not sure about synchotron.
- dekhn 4y agoI mean, I know this is possible- I've definitely seen maps from very high quality (<.8A) crystals that clearly had defined bumps on the heavy atoms that were where you'd expect the hydrogens to be, and later on, neutron scattering confirmed it. But the only times I've seen this it was world-class competitive groups trying to elucidate the specific enzymatic pathway for a protein of industrial interest.