3 ms·
The most powerful results in science are continually reproduced by being built upon to uncover further new knowledge. I'm no expert in the toxic oligomer hypoth
by axg11 4y ago
The most powerful results in science are continually reproduced by being built upon to uncover further new knowledge. I'm no expert in the toxic oligomer hypothesis or Aβ hypothesis, but it appears that these paths have led to very little new knowledge.
- api 4y agoIt reminds me of the eating cholesterol hypothesis for artery blockage and heart disease. Most artery blockages are made of cholesterol therefore eating cholesterol must be the culprit. Simple, straightforward, and now apparently wrong. The cholesterol buildup is a symptom of something else. Seems likely with Alzheimers that the amyloid buildup is a symptom not a cause.
- ramraj07 4y agoStill half a billion dollars of NIH money went into this sub field. The article points to how the main accused got an R01 approved AFTER this misconduct started to come out, and the guy awarding it was one of the coauthors of the first fabricated papers.