3 ms·
> there is lots of data to suggest elevated LDL is a risk of cardiovascular disease Elevated LDL is a symptom of inflammation. It is not a cause and lowering i
by chx 4y ago
> there is lots of data to suggest elevated LDL is a risk of cardiovascular disease
Elevated LDL is a symptom of inflammation. It is not a cause and lowering it doesn't help. The research mixed up cause vs correlation.
- toomuchtodo 4y agoHigh sugar diet the cause (“Western Die” and whatnot)?
- refurb 4y agoI love reading medical advice on HN. Genetic errors which cause high LDL levels result in significant cardiovascular disease. It's a very strong cause and effect. I won't argue that inflammation doesn't play some role (it seems to play a role in many diseases), but I wouldn't dismiss current medical opinion on LDL. https://en.wikipedia.org/wiki/Familial_hypercholesterolemia https://en.wikipedia.org/wiki/Familial_hypercholesterolemia Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL cholesterol), in the blood and early cardiovascular disease.
- imtringued 4y agoWhy aren't you adjusting for LDL subfractions? Seriously, yes having too much LDL can be a sign of having harmful subfractions but that doesn't mean high LDL actually is harmful or low LDL is healthy.
- refurb 4y agoI'm not sure that changes my argument than "There's no such thing as good / bad cholesterol." is a false statement?