5 ms·
Mark Pimentel's lab which studies disorders of the gut has hypothesized that people with extremely slow transit times can absorb 2-3x the amount of energy from
by nikkwong 4y ago
Mark Pimentel's lab which studies disorders of the gut has hypothesized that people with extremely slow transit times can absorb 2-3x the amount of energy from food in comparison to people with regular transit times. I think there is a high amount of variability; and importantly in the context of losing weight, people who are overweight often have slow intestinal transit due to their dysregulated gut microflora.
I'm sort of with you, but it sounds more to me like: start eating less, and you'll lose weight; eat more, and you'll gain weight. There's just too many variables here that change how food is metabolized and digested; including the microbiome which CICO ignores.
- trentgreene 4y agoYou got a source for that study? A cursory google didn’t reveal anything and 2-3x is suspect. To your second point, wouldn’t the microbiome (and slow digestion) just be another input into CICO?
- fsckboy 4y agois it just caloric absorption, or are various essential nutrients also absorbed more and less? asking because coffee can speed up my transit time dramatically, and I'm always down for cutting calories!
- nikkwong 4y agoAFAIK this has not been studied, but I would assume that nutrient absorption could feasibly vary with motility speed just like energy absorption. For example people with chronic diarrhea are usually deficient in several B vitamins especially B12, although their poor absorption may not be only due to rapid transit time and could stem from other gut issues. Rapid transit time is certainly a factor though.